Results 261 to 270 of about 384,922 (349)

Progress of metabolomics‐centric multi‐omics research in medicine

iMetaOmics, EarlyView.
The graphical abstract illustrates a holistic roadmap for metabolomics‐centric multi‐omics integration in medical research. The upper panel depicts the technological transition from traditional bulk analysis to high‐resolution single‐cell and spatial methodologies, specifically addressing inherent challenges such as molecular complexity and dynamic ...
Ziyi Wang, Shiwen Deng, Xiaoxu Wang, Xiao Chang, Na Guo, Peng Chen, Hongjun Yang   +6 more
wiley   +1 more source

A cocktail of SARS-CoV-2 S stem helix domain and receptor binding domain human monoclonal antibodies prevents the emergence of viral escape mutants. [PDF]

Microbiol Spectr
Ma Y, Ye C, Piepenbrink MS, Mahmoud SH, Cupic A, Castro E, Jackson N, Bayoumi M, Padron AS, García-Sastre A, Ippolito GC, Walter MR, Kobie JJ, Martinez-Sobrido L.   +13 more
europepmc   +1 more source

Beyond “you are what you eat”: Unlocking gut microbiota‐mediated biotransformation of dietary phytochemicals

iMetaOmics, EarlyView.
The “efficacy paradox” of phytochemicals, low bioavailability yet significant health benefits, is associated with gut microbiota, which biotransforms dietary precursors into bioactive metabolites, enabling systemic effects. Thus, health outcomes of diet depend not just on intake “the rainbow”, but on gut microbial metabolism, redefining “you are what ...
Peng Yang, Ren‐You Gan
wiley   +1 more source

From hepatitis misdiagnosis to zoonotic false alarms: a metagenomic blacklist framework for the parvo-like hybrid viral group. [PDF]

Microbiol Spectr
Zhao P, Liu H, Dong J, Su H, Jin Q, Yang F.   +5 more
europepmc   +1 more source

Papilloedema with peripapillary retinal haemorrhages in an acquired immunodeficiency syndrome (AIDS) patient with cryptococcal meningitis

Indian Journal of Ophthalmology, 2000
Battu Rajani, Biswas Jyotirmay, ]ayakumar Navin, Madhavan Hajib, Kumarsamy N, Suniti Solomon   +5 more
doaj  

L‐EasyARG: A long‐read metagenomics tool for rapid antibiotic‐resistance‐gene profiling

iMetaOmics, EarlyView.
L‐EasyARG is a pipeline for long‐read metagenomic profiling of antibiotic resistance genes (ARGs) and their genetic context. It integrates ARG identification, plasmid and mobile genetic element (MGE) detection, taxonomic classification, and further identifies ARGs carried by human bacterial pathogens (HBPs) defined in the WHO and ESKAPE pathogen lists.
Yongxin Li, Mingchao Wang, Xiaohui Liu, Junhua Wu, Yujie Mao, Caili Zhang, Qingru Chen, Zhi Wang, Gongchao Jing, Maozhen Han   +9 more
wiley   +1 more source

Near-complete genome sequences of human enterovirus A71 genotype A (BrCr-like) isolates from hand, foot, and mouth disease patients in India. [PDF]

Microbiol Resour Announc
Jagtap K, Sawant PM, Mathapati B, Roy S, Sharma V, Gogoi P, Panickan S, Lavania M.   +7 more
europepmc   +1 more source

The mediating roles of gut microbiota in the associations of air pollution and meteorological factors with metabolic syndrome

iMetaOmics, EarlyView.
We characterized distinct gut microbial community clusters associated with metabolic syndrome (MetS) and identified key genera underlying these patterns. Health‐associated clusters were dominated by beneficial genera such as Bacteroides and Prevotella with known metabolic protective functions.
Yixiang Huang, Wei Wu, Yuan Zheng, Hongwei Tu, Yiping Duan, Qijiong Zhu, Zhiqing Chen, Siwen Yu, Yayi Li, Wan Peng, Wenjun Ma, Tao Liu   +11 more
wiley   +1 more source

Correction: The first trimester human placenta responds to Zika virus infection inducing an interferon (IFN) and antiviral interferon stimulated gene (ISG) response. [PDF]

Virol J
Van der Hoek KH, Jankovic-Karasoulos T, McCullough D, Coldbeck-Shackley RC, Eyre NS, Roberts CT, Beard MR.   +6 more
europepmc   +1 more source

Integrated high‐throughput phenomics and transcriptomics uncover the transcriptional mechanisms underlying rice responses to elevated CO2 concentration and cadmium stress

iMetaOmics, EarlyView.
Developing crop varieties with reduced cadmium (Cd) accumulation under elevated carbon dioxide (eCO2) requires hub gene identification and elucidation of its transcriptional mechanisms. Here, we acquired high‐throughput phenotyping of the rice cultivar Nipponbare across six key developmental stages under Cd stress and three eCO2 concentrations.
Weijun Guo, Hanlin Liu, Dongwei Li, Shang Xie, Yichao Mao, Liwen Yang, Cong Li, Weixuan Wang, Jian Tian, Xiaofeng Gu, Li Pu   +10 more
wiley   +1 more source