Results 101 to 110 of about 4,928,095 (257)

Repurposing FDA‐Approved Drugs to Inhibit Fungal PPTases for Broad‐Spectrum Synergy

open access: yesAdvanced Science, EarlyView.
Fungal secondary metabolites serve as crucial virulence effectors; however, the potential of their biosynthetic pathways as antifungal targets remains inadequately comprehended. Repurposed FDA‐approved drugs inhibit fungal PPTase (essential for secondary metabolism) in vivo.
Zili Song   +7 more
wiley   +1 more source

Analysis of Buying, Selling, and Leasing Virtual Land in the Metaverse: A Perspective from Sharia Economic Law

open access: yesUlul Albab: Jurnal Studi dan Penelitian Hukum Islam
This research aims to analyze the position of virtual land buying, selling, and leasing practices using cryptocurrency in the metaverse from the perspective of Islamic economic law. This study uses a descriptive analysis method with a normative juridical
Muhamad Izazi Nurjaman   +3 more
doaj   +1 more source

¿Cómo se aprende una asignatura en la modalidad Virtual?

open access: yes, 2015
El vídeo describe la metodología a seguir en cada una de las asignaturas en la modalidad ...
UC Virtual
core  

Design Rules for Quantitative Control of Intragrain Planar Defects in Halide Perovskites

open access: yesAdvanced Science, EarlyView.
Dose‐budgeted electron microscopy reveals the design rules governing intragrain planar defects in halide perovskites: {112}t ferroelastic twins proliferate with increasing tetragonality and grain size, whereas {111}c twins and stacking faults emerge as the lattice approaches cubic symmetry.
Byeongjun Gil   +3 more
wiley   +1 more source

Digital Governance for Confiscating Crypto-Assets to Settle Tax Liabilities in Indonesia

open access: yesAptisi Transactions on Technopreneurship
The emergence of digital and virtual assets has created new challenges for tax authorities, as taxpayers now possess not only traditional but also digital assets that can be accessed globally through the internet.
Albert Richi Aruan   +2 more
doaj   +1 more source

An Optimized Freeze‐Dry Multimodal Workflow for Sequential Micro‐CT Imaging, Histology, and Molecular Profiling: A Use Case in Human Liver Fibrosis

open access: yesAdvanced Science, EarlyView.
Optimized freeze‐drying and eosin staining deliver artifact‐free micro‐CT images of liver tissue at near‐histological detail, then hand the same specimen back for sectioning, staining, and sequencing. Fibrotic volume distinguishes normal liver from cirrhosis, while preserved RNA reveals inflammatory gene upregulation—one biopsy, three dimensions, and a
Kristijan Skok   +13 more
wiley   +1 more source

Valuation, Accounting Principles, and Classification of Assets in the Metaverse

open access: yesJournal of Metaverse
This study explores the valuation methods, accounting principles, and asset classification systems needed for accurate financial reporting in the Metaverse.
Meryem Akın, Isik Akin
doaj   +1 more source

Concept, legal nature and classification of virtual assets

open access: yes, 2023
Входження цифрових активів в економічний простір на національному та міжнародному рівнях є інновацією у фінансовій системі. Стрімке проникнення віртуальних активів в економічну сферу сприймається неоднозначно, адже їх унікальність, яка виражається в ...
Цукан, С. В.
core  

Chemotherapy‐Activated GSK3β‐DNMT1 Signaling Upregulates CD47 to Evade Macrophage Phagocytosis and Drive Temozolomide Resistance in Glioblastoma

open access: yesAdvanced Science, EarlyView.
Temozolomide treatment activates GSK3β, driving DNMT1 phosphorylation, destabilization, and CD47 promoter hypomethylation in glioblastoma. This epigenetic shift upregulates CD47, enabling TMZ‐treated GBM cells to evade macrophage phagocytosis, survive chemotherapy, and acquire resistance.
Jie Li   +11 more
wiley   +1 more source

Targeting LDHA Palmitoylation Sensitizes GBM to Chemoradiotherapy via Suppressing Palmitic Acid Induced Glycolytic Reprogramming

open access: yesAdvanced Science, EarlyView.
Mesenchymal GSCs preferentially uptake palmitic acid, thereby promoting ZDHHC12‐mediated LDHA palmitoylation. This modification enhances LDHA enzymatic activity, drives glycolytic reprogramming, and facilitates exosomal LDHA‐mediated TAM regulation.
Zijie Gao   +20 more
wiley   +1 more source

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