Results 231 to 240 of about 19,051,868 (302)

F7 Drives Gastric Cancer Metastasis Through Anoikis Resistance and Tumor Microenvironment Remodeling

Advanced Science, EarlyView.
ABSTRACT Coagulation factor VII (F7) has been implicated in tumor progression; however, its role in gastric cancer metastasis and immune evasion remains incompletely understood. In this study, we identified F7 as a clinically relevant driver of gastric cancer.
Lei Gao, Qinying Han, Yunpeng Wang, Xuemei Li, Bofang Wang, Baohong Gu, Weidong Li, Lin Xiang, Ying Zhang, Hao Chen   +9 more
wiley   +1 more source

Age-Friendly Telegeriatrics: Evidence and a 5M-Based Framework for Hybrid Geriatric Care in Saudi Arabia. [PDF]

Cureus
Alsaad SM.
europepmc   +1 more source

EP300‐Mediated MTF1‐K218 Lactylation Buffers AR‐Driven Copper Overload to Suppress Cuproptosis in Castration‐Resistant Prostate Cancer

Advanced Science, EarlyView.
Androgen receptor (AR) drives copper accumulation in prostate cancer while inducing MTF1 to buffer copper toxicity. EP300‐mediated lactylation of MTF1 at K218 promotes its nuclear translocation and metallothionein expression, sequestering cytosolic copper and preventing mitochondrial cuproptosis.
Kai Li, Yong Wei, Yongshan Li, Yuxiang Dong, Jiancheng Lv, Mingzhi Yuan, Ao Shen, Fuyang Liu, Yetao Zhang, Youjian Li, Ruixi Yu, Yang Liu, Tong Zhao, Jun Wang, Kai Zhou, Zongyao Fan, Manning Wang, Jun Xu, Mulong Du, Min Gu, Bing Yao, Qingyi Zhu   +21 more
wiley   +1 more source

Bridging Pedagogy and Technology: A Systematic Literature Review on Inquiry-Collaborative Models Assisted with Virtual Laboratory in Physics Education. [PDF]

F1000Res
Yahya F, Rusijono R, Dewi U, Metafisika K, Lestiani W, Hermansyah H, Asbanu DESI.   +6 more
europepmc   +1 more source

Neuromorphic Devices and Computing for Sensing, Memory, and Control

Advanced Science, EarlyView.
This review introduces neuromorphic devices made from diverse materials. These devices mimic neuronal functions and architectures and, when integrated with artificial or biological computing, can form closed loops with neurons for pressure, optical, acoustic, and biochemical sensing and modulation.
Zhengguang Zhu, Nicholas Schaffer, Xiao Yang   +2 more
wiley   +1 more source

Voice-Enabled Virtual Patients for Interactive Training in Standardized Clinical Assessment: Mixed Methods Pilot Study. [PDF]

J Med Internet Res
Bossio Botero V, Yadav V, Ouyang J, Abbas A, Worthington M.   +4 more
europepmc   +1 more source

Fusing Direct and Indirect Measurements Through Multi‐Fidelity Learning For Accelerated Electrocaloric Materials Discovery

Advanced Science, EarlyView.
A multi‐fidelity framework integrates sparse direct and abundant indirect electrocaloric measurements. Multi‐objective active learning accelerates BaTiO3‐based electrocaloric materials discovery at –70∘C$^{\circ }{\rm C}$. A diffuse transition enables an electrocaloric strength of 0.06×$\times$10−6 Km/V at –70℃ with an operational temperature span of ...
Bo Wang, Pengfei Dang, Yuan Tian, Zhengwang He, Wei Gu, Lixue Zhang, Turab Lookman, Yumei Zhou, Dezhen Xue   +8 more
wiley   +1 more source

Estimation of Respiratory Volumes During Tidal Breathing Using Two Depth Cameras. [PDF]

Sensors (Basel)
Handley A, Preece S, Tresadern P.
europepmc   +1 more source

Feasibility of large-scale in silico transcatheter aortic valve implantation trials using a fast-to-evaluate model. [PDF]

Biomech Model Mechanobiol
Verstraeten S, van Driel M, Willems R, Divi S, Hoeijmakers M, van de Vosse F, Verhoosel C, Huberts W.   +7 more
europepmc   +1 more source

AI-Enhanced Virtual Simulation as an Adjunct to Skills Laboratory and Clinical Training in Radiography Education: A Commentary from Somalia and Other Resource-Constrained Settin. [PDF]

Adv Med Educ Pract
Mohamed ZA.
europepmc   +1 more source