Results 181 to 190 of about 2,058,920 (369)

DNA‐PKcs‐Driven YAP1 Phosphorylation and Nuclear Translocation: a Key Regulator of Ferroptosis in Hyperglycemia‐Induced Cardiac Dysfunction in Type 1 Diabetes

open access: yesAdvanced Science, EarlyView.
In the context of chronic hyperglycemia, a DDR is initiated, leading to the pathological activation of DNA‐PKcs in the diabetic heart. This activated DNA‐PKcs directly interacts with and phosphorylates YAP1 at Thr226, thereby increasing the nuclear expression of YAP1.
Junyan Wang   +10 more
wiley   +1 more source

Virtual Reality Applied to Hepatic Surgery Simulation: The Next Revolution

open access: green, 1998
Jacques Marescaux   +8 more
openalex   +2 more sources

Solaris Virtual Reality

open access: yes, 2019
The UW Shell Visualization Center is host to the C.A.V.E. (Cave Automatic Virtual Environment), a $2 million piece of virtual reality equipment that allows multiple people to see the same simulation. The floor and three walls are projected upon in order to immerse up to four operators in virtual reality. The C.A.V.E.
openaire   +3 more sources

Uncover Hidden Physical Information of Soft Matter by Observing Large Deformation

open access: yesAdvanced Science, EarlyView.
Detecting internal abnormalities in soft matter remains challenging due to its heterogeneous nature. This study introduces a method that infers hidden physical properties by matching observed deformation with simulation through parallel Bayesian optimization.
Huanyu Yang   +9 more
wiley   +1 more source

Virtual reality in medicine

open access: green, 1999
Gábor J. Székely, Richard M. Satava
openalex   +2 more sources

TRIM25‐Mediated INSIG1 Ubiquitination Promotes MASH Progression Through Reprogramming Lipid Metabolism

open access: yesAdvanced Science, EarlyView.
TRIM25‐mediated ubiquitination of INSIG1 serves as a key driver of lipid metabolism dysregulation in MASH progression. It identifies a novel small‐molecule inhibitor, C27H26N2O4S, which effectively inhibits TRIM25 activity, reducing lipid accumulation and inflammation.
Hao Zhang   +8 more
wiley   +1 more source

Advancements in Bio‐Integrated Flexible Electronics for Hemodynamic Monitoring in Cardiovascular Healthcare

open access: yesAdvanced Science, EarlyView.
This review explores the cutting‐edge development of bio‐integrated flexible electronics for real‐time hemodynamic monitoring in cardiovascular healthcare. It covers key physiological indicators, innovative sensing mechanisms, and materials considerations. This paper highlights the application of both invasive and non‐invasive devices in cardiovascular
Ke Huang, Zhiqiang Ma, Bee Luan Khoo
wiley   +1 more source

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