Results 311 to 320 of about 3,048,260 (392)

Advancing the Tendinopathy Triad: Comment on “Tendinopathy: The Interplay Between Mechanical Stress, Inflammation, and Vascularity”

open access: yesAdvanced Science, EarlyView.
Abstract Building upon the integrative framework of tendinopathy proposed by Gehwolf et al.—which elegantly connects mechanical stress, inflammation, and vascularity—this commentary extends the discussion by introducing novel mechanistic insights and future research directions that move beyond the established triad. A paradigm shift is proposed ...
DuJiang Yang   +3 more
wiley   +1 more source

Virtual reality for stroke rehabilitation. [PDF]

open access: yesCochrane Database Syst Rev
Laver KE   +6 more
europepmc   +1 more source

Colorectal Cancer Cell's Weapon: RNF32 Engages SPP1+ Macrophages to Foster Liver Metastasis, Targeted by Indole‐3‐Acetic Acid

open access: yesAdvanced Science, EarlyView.
Cytoplasmic RNF32 fuels CRC liver metastasis by degrading GSK3β, which stabilizes β‐catenin and activates Wnt/EMT. Moreover, RNF32 rewires the metastatic niche: it depletes CD8+/CD4+ T and NK cells while recruiting SPP1+ macrophages (which boost tumor stemness via CD44), fibroblasts, and immunosuppressive monocytes to aid colonization.
Hongyu Wang   +12 more
wiley   +1 more source

Quantitative Stain Mapping in X‐Ray Virtual Histology

open access: yesAdvanced Science, EarlyView.
Virtual histology promises 3D tissue examination without physical sectioning, yet has lacked the tissue‐specificity of conventional pathology. This work demonstrates the first quantitative three‐dimensional stain mapping at histologically relevant resolution, separating contrast agent from tissue to reveal cellular features such as nuclei. The approach
Dominik John   +16 more
wiley   +1 more source

Virtual reality navigation for the early detection of Alzheimer's disease. [PDF]

open access: yesFront Aging Neurosci
Shima S   +16 more
europepmc   +1 more source

Enhanced Responsivity, Accuracy, and Stability of Aerosol Jet Printing via Mechanical Switching Valve Assisted Internal Shuttering

open access: yesAdvanced Science, EarlyView.
This work demonstrates ultra‐high ON‐OFF responsivity of AJP by mechanical switching valve assisted shuttering. The jet relaxation and ON‐OFF delay are substantially eliminated from greater than 35 s, maintaining patterning quality independent of the variations of printing parameters, permitting excellent process stability and universality.
Jinhang Wang   +6 more
wiley   +1 more source

Personalized virtual reality in hemodialysis patients: a multicenter pilot study. [PDF]

open access: yesClin Kidney J
Russ P   +11 more
europepmc   +1 more source

Multimodal AI‐Driven Identification of Dehydrocostus Lactone as a Potent Renal Fibrosis Attenuator Targeting IQGAP1

open access: yesAdvanced Science, EarlyView.
Renal fibrosis, a hallmark of CKD, lacks effective treatments. Herein, we developed a multimodal AI model (TCM‐SPred) to identify anti‐fibrotic agents and found that dehydrocostus lactone (DCL) targets IQGAP1 to inhibit Wnt signaling, blocking the interaction between IQGAP1 and CCT3, demonstrating potent anti‐fibrotic activity in vitro and in vivo ...
Weijiang Lin   +12 more
wiley   +1 more source

Pilot comparison of monocular and binocular modes of virtual reality field testing in strabismus. [PDF]

open access: yesSci Rep
Liu J   +9 more
europepmc   +1 more source

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