Results 101 to 110 of about 5,773,364 (265)

Structure-based virtual screening for TRPM8 modulators

Frontiers in Drug Discovery
Transient receptor potential melastatin 8 (TRPM8) is an emerging therapeutic target, yet the performance of available structural models for docking and optimal docking protocols for virtual screening (VS) remains unclear.
Nivya James, Pedro J. Ballester
doaj   +1 more source

Phase 1 implementation of nutrition screening in a Dublin acute teaching hospital

, 2014
Nutrition Screening Week results from 2010 and 2011 indicated that one in three to four patients admitted to Irish Hospitals are at risk of disease-related malnutrition, 74-75% of whom are at high risk1.
Nutrition Screening Steering Group
core  

Virtual screening with AutoDock: theory and practice

, 2010
Importance of the field: Virtual screening is a computer-based technique for identifying promising compounds to bind to a target molecule of known structure.
Goodsell DS, Harris R, Perryman AL, COSCONATI, Sandro, Olson AJ, Forli S   +5 more
core   +1 more source

Parity‐Dependent THz Harmonic Generation in Electrically Pumped Micro‐Lasers Exploiting Topological Insulator–Metamaterial Gratings

Advanced Materials, EarlyView.
Topological insulator–metamaterials integrated with electrically driven terahertz quantum cascade lasers enable parity‐dependent harmonic generation. Bulk‐dominated Bi2Se3 favors third‐harmonic emission at 9.96 THz, whereas topological‐surface‐state‐dominated Bi2Se3, Bi2Te3, and (Bi,Sb)2Te3 generate strong second harmonics near 6.5 THz.
Alessandra Di Gaspare, Craig S. Knox, Ahmet Yagmur, Sara Ghayeb Zamharir, Lianhe Li, Satoshi Sasaki, A. Giles Davies, Edmund H. Linfield, Joshua R. Freeman, Miriam S. Vitiello   +9 more
wiley   +1 more source

Breaking Bottlenecks in Solid Electrolyte Discovery With Large Artificial Intelligence Models

Advanced Materials, EarlyView.
Large AI models are presented as a route to break key bottlenecks in solid electrolyte discovery by linking materials databases, machine‐learning interatomic potentials, large language models, and autonomous experiments. This perspective highlights how AI can accelerate the identification of solid electrolytes with fast ion transport, stable interfaces,
Eric Jianfeng Cheng, Min Hong, Zhiquan Zeng, Chuanyu Liu, Qian Wang, Melissa Jane Meadowcroft, Vlad Badilita, Carlos Miguel Costa, Senentxu Lanceros‐Méndez, Ying Li, Chenyao Ma, Weibo Gong, Surendra Kumar Martha, Aloysius Soon, Piao Ma, Di Zhang, Teguh Ariyanto, Sudaryanto, Hiroshi Kakinuma, Jie Zhao, Jiayu Peng, Pengfei Ou, Jun Lu, Shin‐ichi Orimo, Hao Li   +24 more
wiley   +1 more source

Minutes of the Meeting of the Steering Group for National Breast Screening Programme

, 1997
Minutes of a meeting of the Steering Group for National Breast Screening Programme ...
National Breast Screening Group
core  

Flow chart of Virtual screening, pharmacophore-based filtering and experimental screening strategy for identifying efflux inhibitors.

, 2014
Flow chart of Virtual screening, pharmacophore-based filtering and experimental screening strategy for identifying efflux inhibitors.
Kesavan Dineshkumar (598243), Devadasan Velmurugan (598245), Narasumani Mohanalakshmi (598244), Waheeta Hopper (598246), Vasudevan Aparna (598242)   +4 more
core   +1 more source

Reduced Graphene Oxide Enhances the Vascular Organization and Contractile Performance of Fibrin‐Gelatin‐Based Engineered Cardiac Tissue

Advanced Materials Interfaces, EarlyView.
Fibrin–gelatin hydrogels functionalized with reduced graphene oxide create a mechanically stable and bioactive 3D environment for engineered cardiac tissue. The composite matrix promotes endothelial lumen formation, enhances sarcomeric protein expression, and increases contractile performance of embedded cardiomyocytes.
Christoph Kuckelkorn, Marie Baiker, Yajuan Jiang, Ebru Aksoy, Kurt Pfannkuche, Horst Fischer   +5 more
wiley   +1 more source

Beyond Passivation: Designing Structurally Tailored Artificial Interphases for High‐Energy Lithium‐Based Anodes

Advanced Materials Interfaces, EarlyView.
This review outlines critical engineering design rules for building artificial protective coatings on next‐generation lithium metal and silicon battery anodes. It highlights how balancing structural flexibility with strict electronic and ionic transport limits prevents early battery failure.
Surin Gupte, Vilas G. Pol
wiley   +1 more source

High Throughput Aerosol Jet Printing to Operationalize High Aspect Ratio Patterning

Advanced Materials Technologies, EarlyView.
High‐throughput aerosol jet printing poses distinct limiting mechanisms to the printing process. These include rapidly changing ink chemistries, atomization instabilities, and liquid‐phase spreading. The combination of in‐line heating, process monitoring, and traditional optimization procedures enables rapid printing of high‐aspect‐ratio structures ...
Bella I. Guyll, Md Mahdi Ul Ishtiaque, Md Ramjan Ali, Todd A. Kingston, Ethan B. Secor   +4 more
wiley   +1 more source