Results 141 to 150 of about 2,795,372 (389)

Virtual Screening of Acetylcholinesterase Inhibitors [PDF]

, 2012
AD is associated with low in vivo level of acetylcholinesterase. The consistent neuropathologic hallmark of the disorder is a massive deposit of aggregated protein degradation products, amyloid-β (Aβ) plaques and neurofibrillary tangles (Haviv et al., 2005).
Jiang Yu-ren, Li Chuan-jun, Pan Ya-fei, Chen Dan, Xie Yun-feng   +4 more
openaire   +3 more sources

Van Der Waals Hybrid Integration of 2D Semimetals for Broadband Photodetection

Advanced Materials, EarlyView.
Advanced broadband photodetector technologies are essential for military and civilian applications. 2D semimetals, with their gapless band structures, high mobility, and topological protection, offer great promise for broadband PDs. This study reviews the latest advancements in broadband PDs utilizing heterostructures that combine 2D semimetals with ...
Xue Li, Kunxuan Liu, Di Wu, Pei Lin, Zhifeng Shi, Xinjian Li, Longhui Zeng, Yang Chai, Shu Ping Lau, Yuen Hong Tsang   +9 more
wiley   +1 more source

CONSTRUCTION AND RETROSPECTIVE VALIDATION OF STRUCTURE-BASED VIRTUAL SCREENING PROTOCOLS TO IDENTIFY POTENT LIGANDS FOR HUMAN ADRENERGIC BETA-2 RECEPTOR

Indonesian Journal of Pharmacy, 2015
Adrenergic Beta-2 Receptor (ADRB2) is a member of G- protein coupled receptors family, which has served as targets for more than 30% of top-selling drugs in the market.
Enade Perdana Istyastono, Dewi Setyaningsih3   +1 more
doaj   +1 more source

Radiologist sees a future for virtual colonoscopy as screening tool [PDF]

, 2001
D. Gordon
openalex   +1 more source

Prediction by Nonparametric Posterior Estimation in Virtual Screening

, 2007
The ability to rank molecules according to their effectiveness in some domain, e.g. pesticide, drug, is important owing to the cost of synthesising and testing chemical compounds.
Pasupa, Kitsuchart
core  

Parsimonious Kernel Fisher Discrimination

, 2007
By applying recent results in optimization transfer, a new algorithm for kernel Fisher Discriminant Analysis is provided that makes use of a non-smooth penalty on the coefficients to provide a parsimonious solution.
A. Leach, B. Chen, B. Krishnapuram, B. Schölkopf, D.R. Hunter, G. Harper, G. Rätsch, K. Lange, K.C. Kiwiel, R. Dutter, R.O. Duda, S.A. Billings   +11 more
core   +1 more source

Advances in Photonic Materials and Integrated Devices for Smart and Digital Healthcare: Bridging the Gap Between Materials and Systems

Advanced Materials, EarlyView.
This article summarizes significant technological advancements in materials, photonic devices, and bio‐interfaced systems, which demonstrate successful applications for impacting human healthcare via improved therapies, advanced diagnostics, and on‐skin health monitoring.
Seunghyeb Ban, Hoon Yi, Jaejin Park, Yunuo Huang, Ki Jun Yu, Woon‐Hong Yeo   +5 more
wiley   +1 more source

Influences on participation in a community‐based colorectal neoplasia screening program by virtual colonoscopy in Australia

Australian and New Zealand Journal of Public Health, 2004
Objective: To determine the effect of certain personal and health behaviour characteristics on participation in a community‐based colorectal neoplasia (CRN) screening program using virtual colonoscopy.
Geoffrey M. Forbes, Lin Fritschi, Richard M. Mendelson, Noellene M. Foster, John T. Edwards   +4 more
doaj   +1 more source

Virtual Screening in Lead Discovery: A Viewpoint [PDF]

, 2002
Tudor I. Oprea
openalex   +1 more source

Hidden bias in the DUD-E dataset leads to misleading performance of deep learning in structure-based virtual screening

PLoS ONE, 2019
Recently much effort has been invested in using convolutional neural network (CNN) models trained on 3D structural images of protein-ligand complexes to distinguish binding from non-binding ligands for virtual screening.
Lieyang Chen, Anthony Cruz, Steven Ramsey, Callum J. Dickson, J. Duca, V. Hornak, D. Koes, T. Kurtzman   +7 more
semanticscholar   +1 more source