Results 171 to 180 of about 6,233,093 (291)

Synergies of Geospatial and Digital Technologies for Sustainable Rural Development: A Data‐Driven Analysis of Topics and Novelty Assessment

open access: yesSustainable Development, EarlyView.
ABSTRACT The adoption of geospatial and digital technologies, including Geographic Information Systems (GIS), Building Information Modelling (BIM), Digital Twins, the Internet of Things (IoT) and Artificial Intelligence (AI), is increasingly recognised as key enablers of sustainable development.
Monica C. M. Parlato, Andrea Pezzuolo
wiley   +1 more source

Innovative 3D‐bioprinted microfibers in calcium phosphate cement platform with Nell‐1 to activate nerve‐bone axis for synergistic bone, vasculature, and nanofibrous nerve regeneration

open access: yesSmart Molecules, EarlyView.
A 3D‐bioprinted platform with stem cells activates “nerve‐bone” signaling by enabling the spatiotemporal delivery of Nell‐1. This activation enhances neurovascular and bone regeneration through the CYFIP1 cascade. In rat calvarial defects, the platform doubled bone regeneration and nerve repair and tripled vascular density, resulting in superior ...
Minjia Zhu   +11 more
wiley   +1 more source

Artificial intelligence empowers targeted protein degradation: Core technological innovations, multi‐scenario applications, and translational prospects

open access: yesSmart Molecules, EarlyView.
AI is transforming TPD by improving the design, prediction, and optimization of degraders such as PROTACs, molecular glues, and LYTACs. This review summarizes key AI‐driven advances, highlights applications across drug discovery stages, and discusses remaining challenges and future directions for accelerating the development of therapies against ...
Shuanglin Qin   +10 more
wiley   +1 more source

Programmable Porosity in Polymers via Microfluidic Templating and 3D Printing

open access: yesSmall Methods, EarlyView.
Fluid templating is a powerful way to produce porous polymers. Microfluidic technologies enable fine control over the dimension and packing of bubbles and droplets. Combined with additive manufacturing, microfluidic templating enables the creation of polymeric functionally graded porous materials in which both porosity and three‐dimensional geometry ...
Federico Serpe   +3 more
wiley   +1 more source

Microfluidic Molecular Diagnostic Chips: Functional Modules, Integration Strategies, and Emerging Applications

open access: yesSmall Methods, EarlyView.
This comprehensive review delivers an engineering‐centric analysis of microfluidic molecular diagnostic chips, breaking them down into foundational modules from fluid manipulation to bio‐sensing. Beyond chip design, it evaluates sample‐to‐answer integration strategies and commercial readiness levels.
Donghoon Koo   +7 more
wiley   +1 more source

Contemporary and Future Challenges for Structured Democratic Dialogue

open access: yesSystems Research and Behavioral Science, EarlyView.
ABSTRACT Structured Democratic Dialogue (SDD) is a participatory problem structuring methodology grounded in Structured Dialogic Design Science. It was created to help diverse stakeholders co‐construct influence maps that reveal leverage points and support coordinated action.
Yiannis Laouris, Gerald Midgley
wiley   +1 more source

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