USP5 Stabilizes TGFBR1 to Drive Vascular Smooth Muscle Cell Senescence and Atherosclerosis
This study reveals that USP5 drives vascular smooth muscle cell senescence and atherosclerosis by stabilizing TGFBR1, suppressing IDH2, and promoting glycolytic reprogramming, identifying the USP5‐TGFBR1‐IDH2 axis as a potential therapeutic target. ABSTRACT Vascular smooth muscle cell (VSMC) senescence contributes importantly to atherosclerotic plaque ...
Xinhai Cui +5 more
wiley +1 more source
Usability, acceptability, and tolerability of a virtual reality patient tour compared to an educational video in cardiac surgery patients - A feasibility study. [PDF]
Cardol CM +4 more
europepmc +1 more source
FBL directly binds to and stabilizes SIRT1 by blocking its ubiquitin‐proteasome degradation, thereby sustaining nicotinamide metabolism and redox homeostasis to counteract cellular senescence in ESCC. Genetic and pharmacological suppression of FBL sensitizes tumor cells to senolytic therapy.
Xing Jin +9 more
wiley +1 more source
Efficacy of virtual reality interventions in reducing preoperative anxiety in pediatric patients undergoing general anesthesia: a systematic review and meta-analysis. [PDF]
Song J, Tu Y, Chen Q, Bao R, Ye X.
europepmc +1 more source
A self‐powered vibration sensing platform integrates a quasi‐zero‐stiffness piezoelectric harvester, synchronized electric charge extraction, energy management, and wireless ADC acquisition. Ambient vibration is simultaneously harvested as energy and digitized as information, enabling sustained real‐time waveform monitoring without external power.
Yizhou Li +10 more
wiley +1 more source
A Methodological Case Study for Integrating Virtual Reality and 3D Photogrammetry: A Pilot Digital Platform for Exploring Mangrove Environments. [PDF]
Ng TPT +6 more
europepmc +1 more source
A large‐area, noise‐resilient multiplexed triboelectric sensing garment based on a multilayer shielded architecture and SnS2 nanoflower‐engineered hybrid materials enables interference‐suppressed, high‐fidelity full‐body motion tracking, achieving 0.13% signal misrecognition, 57 dB electromagnetic noise attenuation, and >1.5 N threshold force, while ...
Beibei Shao +14 more
wiley +1 more source
Single-Center Pilot Evaluation of Virtual Vascular Surgery Rotation in Retention of Knowledge and Skills. [PDF]
Harding J +6 more
europepmc +1 more source
Oxygen vacancy migration is a key degradation mechanism for the majority of MLCCs. There are limitations with spatially identifying regions of a capacitor that have degraded due to oxygen vacancy migration. This work showcases ultrasonic attenuation as a non‐electrical and nondestructive technique of identifying oxygen vacancy degraded regions of an ...
Haley N. Jones +3 more
wiley +1 more source
Perioperative virtual reality and neuropsychiatric outcomes: a scoping review. [PDF]
Li H +8 more
europepmc +1 more source

