Results 191 to 200 of about 5,324,367 (334)

Multimodal AI‐Driven Identification of Dehydrocostus Lactone as a Potent Renal Fibrosis Attenuator Targeting IQGAP1

Advanced Science, EarlyView.
Renal fibrosis, a hallmark of CKD, lacks effective treatments. Herein, we developed a multimodal AI model (TCM‐SPred) to identify anti‐fibrotic agents and found that dehydrocostus lactone (DCL) targets IQGAP1 to inhibit Wnt signaling, blocking the interaction between IQGAP1 and CCT3, demonstrating potent anti‐fibrotic activity in vitro and in vivo ...
Weijiang Lin, Wenzhuo Xu, Kang Liu, Ping Wang, Zhenzhen Zhu, Wenyu Lu, Zhe Zheng, Xiaoqian Peng, Xunkai Yin, Shulan Mei, An Pan, Jian Liu, Lihong Hu   +12 more
wiley   +1 more source

The role of virtual training workshops based on the ISO 10015 standard in increasing the health and safety students' knowledge. [PDF]

J Educ Health Promot
Khosravi Z, Mish Mast M, Davoodi F, Hosseini Gousheh SN, Khajehnasiri F, Azmoon MH, Ahangarzadeh M, Eshaghzadeh M, Sahlabadi AS, Askari A, Poursadeghiyan M.   +10 more
europepmc   +1 more source

Material virtual training

Material virtual ...
openaire   +1 more source

Transcription Factor Promiscuity Drives Regulatory Rewiring and Evolvability in Gene Networks in Bacteria

Advanced Science, EarlyView.
ABSTRACT This special issue marking the University of Bath's 60th anniversary offers an opportunity to reflect on nearly a decade of research into the evolution of gene regulatory networks (GRNs) from members of the lab and elsewhere. Our goal is to understand how GRNs rewire and how new transcription factor (TF) functions evolve. Using an experimental
Tiffany B. Taylor, Alan M. Rice
wiley   +1 more source

RCPNEOPERU trial: a cluster randomized pilot trial to assess traditional neonatal resuscitation compared to partially virtual training in remote areas. [PDF]

J Pediatr (Rio J)
Delgado CA, Gómez Pomar E, Velásquez P, Sánchez V, Shimabuku R, Huicho L.   +5 more
europepmc   +1 more source

Reconstructing Coherent Functional Landscape From Multi‐Modal Multi‐Slice Spatial Transcriptomics by a Variational Spatial Gaussian Process

Advanced Science, EarlyView.
This study introduces stVGP, a variational spatial Gaussian process framework for multi‐modal, multi‐slice spatial transcriptomics. By integrating histological and genomic data through hybrid alignment and attention‐based fusion, stVGP reconstructs coherent 3D functional landscapes.
Zedong Wang, Bowen Fu, Chuanchao Zhang, Xiaoping Liu   +3 more
wiley   +1 more source

Improving the accuracy of emergency department clinicians in detecting SARS-COV-2 on chest X-rays using a bespoke virtual training platform. [PDF]

BMC Med Educ
Bahra J, Acharya A, Ather S, Benamore R, Moreland JA, Gulati D, How L, Rosemarysdottir T, Huwae M, Wilson S, Banerji A, Manso K, Keating L, Barrett A, Gleeson F, Novak A.   +15 more
europepmc   +1 more source

Effectiveness of Virtual Training in the Post-Pandemic Period Using the Kirkpatrick Model

, 2023
Suraj N, N A.
europepmc   +1 more source

Accelerated Discovery of Topological Conductors for Nanoscale Interconnects

Advanced Science, EarlyView.
Copper interconnects exhibit a sharp increase in resistivity at ultra‐scaled dimensions, threatening continued miniaturization of integrated circuits. The gapless surface states of topological semimetals provide conduction channels resistant to localization.
Alexander C. Tyner, William Rogers, Po‐Hsin Shih, Yi‐Hsin Tu, Gengchiau Liang, Hsin Lin, Ching‐Tzu Chen, James M. Rondinelli   +7 more
wiley   +1 more source

Evaluation of virtual training delivery for health information systems implementation in Canada: A qualitative study. [PDF]

Health Inf Manag
Karsan I, Hasan H, Jeyakumar T, Ambata-Villaneuva S, Fur K, Hanley I, McClure S, Omar M, Sheriff T, Wiljer D.   +9 more
europepmc   +1 more source