Results 41 to 50 of about 48,568 (299)

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Can a Highly Virtual Nucleon Experience Final State Interactions in Electron-Nucleus Scattering?

, 1995
We discuss how the virtuality of the struck particle may affect the final state interactions in electron-nucleus scattering. The extent to which short range correlations inhibit rescattering taking place within the range of the repulsive core of the NN ...
Benhar, O., Liuti, S.
core   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

Augmented virtuality technology in education: taxonomy of augmented virtuality types

RUDN Journal of Informatization in Education
Problem statement. The authors discuss the interim results, which analyzed the least of all the studied immersive technologies - augmented virtuality technology and its educational potential.
Alexandr V. Grinshkun, Anastasia S. Zakova   +1 more
doaj   +1 more source

Selfie Culture: A View on Cyber Documentarism [PDF]

Studii si Cercetari de Istoria Artei : Teatru, Muzică, Cinematografie, 2017
The intention of this discussion is to question of documentary form and selfie phenomenon in the cultural implications emerged as a consequence of widespread new technologies and social networking, touchscreen and video.
Lejla Panjeta
doaj  

El desgarramiento del cuerpo postmoderno / The tearing of the postmodern body

Valenciana, 2020
El autor expone el problema del pensamiento y la práctica del mundo occidental posmoderno, donde coinciden la violencia y el abandono de todo soporte natural de los valores. Para buscar una posible solución examina el concepto de
Arturo Rico Bovio
doaj   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

Molecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg, Joachim von Braun, Julio Celis, Anton Berns, Michael Baumann, Tit Albreht, Nancy Abou‐Zeid, Vanderlei Bagnato, Christian Brandts, Chien‐Jen Chen, Massimiliano di Pietro, Manjit Dosanjh, Thomas Dubois, Alexander Eggermont, Angelika Eggert, Ingemar Ernberg, Sara Faithfull, Johannes Förner, Stefan Fröhling, Manuel Heitor, Leroy Hood, Wei Jiang, Bengt Jönsson, Ravi Kannan, Maria Leptin, Su Li, Peter Lindgren, Douglas Lowy, Jun Ma, Alex Markham, Péter Nagy, Simon Oberst, M. Iqbal Parker, Danielle Rodin, Kevin Ryan, Joachim Schüz, Richard Sullivan, Josep Tabernero, Peter Turkson, Oliver Várhelyi, Harold Varmus, Chijie Wang, Elisabete Weiderpass, Nils Wilking   +43 more
wiley   +1 more source

Writing Virtuality: Mu Xin’s Sinographic Designs Across Media and Nations

Writing Chinese: A Journal of Contemporary Sinophone Literature
This article reinterprets the concept of "virtuality" within contemporary Sinophone literature through a study of contemporary Sinophone author Mu Xin (1927-2011)’s writings and media presence. Challenging the common conflation of virtuality with digital
Muyun Zhou
doaj   +1 more source

Virtual Ontology: to the Question of New World Order [PDF]

Философия и космология, 2019
The problem of space and time has a long history of philosophical discussions about the nature of these phenomena. However, the modern era of information and communication technologies opens up new aspects of this problem and the fundamental principles
Chengzhang Zou, Weizhen Gao
doaj   +1 more source

A random walk with heavy flavours [PDF]

, 2013
We focus on evaluating transport coefficients like drag and diffusion of heavy quarks (HQ) passing through Quark Gluon Plasma using perturbative QCD (pQCD).
Bhattacharyya, Trambak, Das, Santosh K., Mazumder, Surasree   +2 more
core   +3 more sources