Results 11 to 20 of about 4,297 (180)
Pharmacological Inhibition of Cav2.2 Channels by Recombinant Phα1β Toxin (CTK01512-2). [PDF]
The recombinant Phα1β toxin (CTK01512‐2) partially and reversibly inhibits Cav2.2 calcium channels in HEK‐293 cells. CTK01512‐2 displays dose‐dependent inhibition of N‐type calcium currents, with an IC50 of 3.94 nM. In vivo, CTK01512‐2 effectively reduces mechanical allodynia in a neuropathic pain model, confirming its antinociceptive activity ...
Carobin NV +5 more
europepmc +2 more sources
Social media governance and strategies to combat online hatespeech in Germany
Abstract Concerns over online hatespeech have prompted governments to strengthen social media governance. However, claims by policy‐makers and political activists regarding the effectiveness and likely consequences of legal regulations remain largely untested.
Daniela Stockmann +2 more
wiley +1 more source
Abstract The African Water Vision 2025 emphasized the disadvantages of the rural population in the context of water supply infrastructure, water management, and access. The vision extolled the virtues of providing improved decentralized governance and localized actions to deliver on this agenda.
Kristin Mutschinski, Neil A. Coles
wiley +1 more source
Gender bias in pediatric care: Health professionals' opinions and perceptions
Abstract Introduction Gender bias in healthcare is understood as a misconception of the differences between males and females that may generate healthcare disparities and discrimination against one sex. However, is not well known how this implicit bias is manifested in pediatric clinical praxis.
Neus Carrilero +3 more
wiley +1 more source
História e Crítica: Gibbon e a “Grandeza imoderada de Roma”
Trata-se de mostrar que, embora se utilize de termos da tópica difundida na querela do luxo, Gibbon realiza sua análise das causas da queda do Império Romano sob uma perspectiva inovadora.
Fernão de Oliveira Salles
doaj +1 more source
A natureza egoísta e a virtude na obra de Bernard Mandeville
Pensar as virtudes em nome do bom funcionamento do Estado supõe enaltecer aquelas que atendam aos interesses do bom convívio, em detrimento de seus opostos.
Elizângela Inocêncio Mattos
doaj +1 more source
Sur Protagoras 351c4-5 et 352b3-c2
In lieu of an abstract, here is a brief excerpt of the content: "Le Protagoras est sûrement l’un des plus beaux dialogues de Platon. Il est traditionnellement placé parmi les dialogues socratiques de Platon, en compagnie, entre autres, du Lachès, de
Marco Zingano
doaj +1 more source
O ESTATUTO DAS PAIXÕES SEGUNDO ARISTÓTELES
A partir de um breve estudo acerca da tipologia das disposições de caracteres (éthos) apresentada na Ética a Nicômaco buscamos estabelecer possíveis relações entre as paixões (páthos) que conduzem aos ditos tipos e à formação do caráter humano. Com essa
Juliana Santana de Almeida
doaj
A natureza da virtude como saber em Platão
The notion of virtue is undoubtedly one of the main components of the ethics of ancient Greek thinkers. Being the privileged instrument for achieving happiness, virtue already played an important role in Archaic Greece.
Guy Hamelin
doaj +1 more source
A QUESTÃO DA NATUREZA NOS DISCURSOS SOBRE AS CIÊNCIAS E AS ARTES E A DESIGUALDADE
No Discurso sobre as ciências e as artes, Rousseau diz que as ciências e as artes contribuíram para a corrupção dos costumes. O que tem a ver a corrupção dos costumes com a natureza conforme expôs neste Discurso?
Manoel Dionizio Neto
doaj +1 more source

