Results 41 to 50 of about 40,172 (292)

On Hierarchical Composite Endpoints in Pediatric Cancer Supportive Care: Illustrative Examples From Two Multi‐Center Phase‐III Randomized Clinical Trials

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric supportive care clinical trials often involve multiple clinically important outcomes, complicating trial interpretation. Hierarchical composite endpoints (HCEs) provide a framework to integrate key outcomes according to clinical importance.
Willem H. Collier, Mark Zobeck, Adam J. Esbenshade, Christopher C. Dvorak, Lillian Sung, David Freyer, Sarah Alexander, Etan Orgel, Nicole J. Ullrich, Zach Prudowsky, Brian Fisher, Caitlin W. Elgarten   +11 more
wiley   +1 more source

Virtue ethics: Beyond moral theory

South African Journal of Bioethics and Law, 2015
In December 2013, a 52 year old man and a practising Jehovah’s Witness  was admitted to Chris Hani Baragwanath Hospital (CHBAH), Soweto, Johannesburg.
Karen Koch, Colin Menezes
doaj   +1 more source

The virtue of Bonhoeffer's ethics: a study of Dietrich Bonhoeffer's Ethics in relation to virtue ethics [PDF]

, 2009
Jennifer Moberly, 'The Virtue of Bonhoeffer's Ethics: A Study of Dietrich Bonhoeffer's Ethics in Relation to Virtue Ethics' (PhD, 2009) This study first explores the prima facie reasons for rejecting the possibility of seeing a close relationship ...
MOBERLY, JENNIFER,LYNNE
core  

Posterior Cortical Atrophy in the Asia‐Pacific: A Report From the PCA Asian Workgroup

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Posterior Cortical Atrophy (PCA) is a distinct dementia syndrome primarily affecting spatial abilities and visual processing. It is associated with degeneration in the posterior part of the brain. PCA is subclassified into PCA‐pure and PCA‐plus syndromes based on consensus criteria.
Yuttachai Likitjaroen, Ya‐Ting Chang, Levinia Lim, Pai‐Yi Chiu, Jung‐Lung Hsu, SangYun Kim, Wataru Narita, Na Young Ryoo, Kyoko Suzuki, Nagaendran Kandiah, Sebastian Crutch, Ming‐Chyi Pai   +11 more
wiley   +1 more source

Filial Piety and Business Ethics: A Confucian Reflection [PDF]

, 2020
This volume examines the breadth and depth of virtue ethics and aims to counter the virtue ethics amnesia that both afflicts general moral philosophy and affects business and management ...
Mondejar, R, Kim, R, Chu, C
core  

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling, Mark D. Parker, Sven Kerst, Richard A. Pasternack, Jacob Tondreau, Marjolein Breur, Gemma M. van Rooijen‐van Leeuwen, Davide Tonduti, Ettore Salsano, Alejandra Darling, Joanna A. E. van Wijk, Susanna Törnroth‐Horsefield, Marianna Bugiani, Petra J. W. Pouwels, Quinten Waisfisz, Marjo S. van der Knaap, Rogier Min   +16 more
wiley   +1 more source

Virtue Ethics and Corporate Governance [PDF]

, 2013
The purpose of this interpretative phenomenological study was to explore directors’ lived experience of ethics in their task of corporate governance so as to capture some of the multiple facets of this phenomenon: specifically how directors understand ...
Grant, Patricia Louise
core  

The Social Virtue Of Blind Deference [PDF]

, 2015
Recently, it has become popular to account for knowledge and other epistemic states in terms of epistemic virtues. The present paper focuses on an epistemic virtue relevant when deferring to others in testimonial contexts.
Ahlstrom-Vij, Kristoffer
core   +1 more source

Paramagnetic Rim Lesions and Choroid Plexus Volume at Diagnosis Are Associated With Cognitive Progression Independent of Relapse and MRI Activity in Early Relapsing–Remitting Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Paramagnetic rim lesions (PRLs) and choroid plexus (CP) enlargement reflect smoldering inflammation in multiple sclerosis. Their role in cognitive progression remains unexplored. Eighty‐seven early relapsing–remitting MS patients were enrolled at diagnosis and followed longitudinally.
Stefano Ziccardi, Damiano Marastoni, Agnese Tamanti, Pietro Biasi, Valentina Visani, Annalisa Colombi, Tom A. Fuchs, Monica Sicchieri, Chiara Eccher, Francesco Guarnaccia, Milena Calderone, Valentina Camera, Francesca Benedetta Pizzini, Roberta Magliozzi, Marco Castellaro, Massimiliano Calabrese   +15 more
wiley   +1 more source

Virtue Ethics and the Environment [PDF]

This book addresses one of today’s most burning issues, namely the environmental crisis, by offering an insight into the problem from the perspective of virtue ethics.
Dzwonkowska, Dominika
core   +1 more source