Results 171 to 180 of about 483,407 (311)

Migration‐Associated Variation in Gastric Cancer Risk in the United States: Implications for Risk Stratification

open access: yesInternational Journal of Cancer, EarlyView.
This study provides contemporary, population‐based evidence that migration‐associated differences in gastric cancer risk, first described decades ago, remain stable, quantifiable, and prevention‐relevant in the United States. By integrating modern cancer registry data with formal trend analysis and conditional extrapolation, the authors show that ...
Chul S. Hyun   +4 more
wiley   +1 more source

Genetic Fingerprint of <i>Klebsiella pneumoniae</i> Virulence: A Systematic Review. [PDF]

open access: yesPathogens
Aldana-Ortega CA   +4 more
europepmc   +1 more source

Prevalence of Helicobacter pylori Exposure and Risk Factors Among BRCA1 and BRCA2 Carriers

open access: yesInternational Journal of Cancer, EarlyView.
BRCA1 and BRCA2 pathogenic germline variant (PGV) carriers may be at increased risk of gastric cancer (GC), especially in the case of prior or active Helicobacter pylori (Hp) infection. The extent to which Hp influences BRCA1 and BRCA2‐associated GC remains uncertain. Here, the authors evaluated plasma samples from a U.S. cohort of BRCA1, BRCA2, PALB2,
Kole H. Buckley   +12 more
wiley   +1 more source

Genomics of Hospital-Associated Brazilian Multidrug-Resistant Klebsiella pneumoniae: Abundance of Resistance and Virulence Genes and Mosaicism of the bla<sub>KPC-2</sub> Genetic Context Among Enterobacterales. [PDF]

open access: yesCurr Microbiol
Pereira MF   +9 more
europepmc   +1 more source

Antibiotic Remodeling of the Gut Microbiota Impairs Host Resistance to Secondary Infection

open access: yesiMetaMed, EarlyView.
Gut microbial dynamics induced by four antibiotics, revealed distinct taxonomic and functional shifts. Vancomycin‐perturbed bacteriomes were proven to promote pathogen resistance to antibiotic treatment. Metronidazole‐treated mice showed pronounced Salmonella translocation to hepatic tissue, and altered Enterococcus avium populations modulated host ...
Miaoyu Li   +17 more
wiley   +1 more source

Substrate Characterization of Mycobacterial Kinase PknG Revealing PknG‐KARS‐MAPK Phosphorylation Signaling Axis in Host

open access: yesiMetaMed, EarlyView.
This study employed multi‐omics approaches to investigate the regulatory mechanism of Mycobacterium PknG on host cell processes. We found that host lysine‐tRNA ligase (KARS) is a potential substrate of PknG; and PknG can regulate the immune response by catalyzing the phosphorylation of KARS at T592 and T595 sites, affecting the phosphorylation level in
Nana Tian   +13 more
wiley   +1 more source

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