The DENN Protein SMD1 Forms a Signalling Hub With Rab GTPase YPT1 to Regulate Diverse Biological Processes in Phytopathogenic Fungi and Serves as a HIGS Target for Crop Protection. [PDF]
Zhang C +5 more
europepmc +1 more source
This study provides contemporary, population‐based evidence that migration‐associated differences in gastric cancer risk, first described decades ago, remain stable, quantifiable, and prevention‐relevant in the United States. By integrating modern cancer registry data with formal trend analysis and conditional extrapolation, the authors show that ...
Chul S. Hyun +4 more
wiley +1 more source
Genetic Fingerprint of <i>Klebsiella pneumoniae</i> Virulence: A Systematic Review. [PDF]
Aldana-Ortega CA +4 more
europepmc +1 more source
Prevalence of Helicobacter pylori Exposure and Risk Factors Among BRCA1 and BRCA2 Carriers
BRCA1 and BRCA2 pathogenic germline variant (PGV) carriers may be at increased risk of gastric cancer (GC), especially in the case of prior or active Helicobacter pylori (Hp) infection. The extent to which Hp influences BRCA1 and BRCA2‐associated GC remains uncertain. Here, the authors evaluated plasma samples from a U.S. cohort of BRCA1, BRCA2, PALB2,
Kole H. Buckley +12 more
wiley +1 more source
Genomics of Hospital-Associated Brazilian Multidrug-Resistant Klebsiella pneumoniae: Abundance of Resistance and Virulence Genes and Mosaicism of the bla<sub>KPC-2</sub> Genetic Context Among Enterobacterales. [PDF]
Pereira MF +9 more
europepmc +1 more source
Virulome Landscape of Multidrug-Resistant <i>Escherichia coli</i> Across Human, Animal, and Environmental Reservoirs. [PDF]
Nnah EP +4 more
europepmc +1 more source
Antibiotic Remodeling of the Gut Microbiota Impairs Host Resistance to Secondary Infection
Gut microbial dynamics induced by four antibiotics, revealed distinct taxonomic and functional shifts. Vancomycin‐perturbed bacteriomes were proven to promote pathogen resistance to antibiotic treatment. Metronidazole‐treated mice showed pronounced Salmonella translocation to hepatic tissue, and altered Enterococcus avium populations modulated host ...
Miaoyu Li +17 more
wiley +1 more source
A synopsis of competence-regulated virulence in <i>Streptococcus pneumoniae</i>. [PDF]
Chong SY, Lew SQ, Lau GW.
europepmc +1 more source
This study employed multi‐omics approaches to investigate the regulatory mechanism of Mycobacterium PknG on host cell processes. We found that host lysine‐tRNA ligase (KARS) is a potential substrate of PknG; and PknG can regulate the immune response by catalyzing the phosphorylation of KARS at T592 and T595 sites, affecting the phosphorylation level in
Nana Tian +13 more
wiley +1 more source
Finding the needle in a haystack: Single amino acids that shape viral virulence. [PDF]
Sanchez DJ.
europepmc +1 more source

