Results 121 to 130 of about 2,295,443 (384)
Advanced Science, EarlyView.This study shows that integrin receptor CD49a (Itga1 gene) is significantly upregulated in hyperactivated microglia and microglia‐specific knockdown of Itga1 rescues neuroinflammation and neurodegeneration in a chronic Parkinson's disease (PD) model by targeting PGAM5‐mediated mitochondrial dysfunction and NLRP3 activation. Targeted inhibition of CD49a
Huanpeng Lu +6 more
wiley +1 more source
3D cell cultures: prospects for use in virology
Инфекция и иммунитетAs a rule, traditional methods of cell cultivation in vitro using monolayer cell lines (2D cultivation) are unable to simulate the structural organization of a three-dimensional (3D) cell network in vivo and are insufficient for modeling living tissues ...
Tatyana A. Kuznetsova +3 more
doaj +1 more source
Проблемы особо опасных инфекций, 2014 /cell, using maintenance media 199 with admixture of 0.1 % human serum albumin or 2 % bovine serum. Optimum media volume in the roll-bottle for fixed rabies virus strain, “Moscow 3253”, cultivation is 200-400 ml. It depends upon the proliferating surface
S. V. Generalov +5 more
doaj +1 more source
The Future of Cydia pomonella Granulovirus in Biological Control of Codling Moth [PDF]
, 2008 Resistance of codling moth against Cydia pomonella granulovirus (CpGV) products has alarmed growers, extension services, the CpGV producers and the scientific community.
Jehle, J. A.
core
Advanced Science, EarlyView.RvD5 effectively alleviates UC by inhibiting STAT1 signaling to reduce CXCL8 expression in colonic epithelial cells via activation of GPR101, which subsequently decreases the infiltration of neutrophils in the colonic mucosal epithelium. Epimedin A1, a natural allosteric inhibitor of 5‐LOX, demonstrates potential as a therapeutic agent for UC by ...
Pengxiang Guo +9 more
wiley +1 more source
The influence of jasmonic acid on the development of virus-free potato plants in vitro
Acta Biologica Slovenica, 1989 The potato plant cv. Vesna tolerates PVM and is systemically infected with this virus. PYM was eliminated by tissue culture. The cultivation of healthy plants was unsuccessful if only the meri stem isolation was used, as virus particles were also found
Maja Ravnikar, Nada Gogala
doaj +1 more source
IFNα and IFNγ Impede Marek’s Disease Progression [PDF]
, 2019 Marek’s disease virus (MDV) is an alphaherpesvirus that causes Marek’s disease, a malignant lymphoproliferative disease of domestic chickens. While MDV vaccines protect animals from clinical disease, they do not provide sterilizing immunity and allow ...
Bertzbach, Luca D. +6 more
core +1 more source
GbWAKL20 Phosphorylates GbNFYB8 to Modulate Verticillium Wilt Resistance in Cotton
Advanced Science, EarlyView.Wall‐associated receptor‐like kinases (WAKLs) play pivotal roles in extracellular–intracellular signal transduction. Upon sensing Verticillium dahliae infestation at the plasma membrane, GbWAKL20 accumulates and transmits signals to the nucleus via endoplasmic reticulum‐mediated Golgi vesicle transport.
Guilin Wang +7 more
wiley +1 more source
TNFα PRODUCTION AND APOPTOSIS REGULATION IN VIRAL HEPATITIS TYPE C
Медицинская иммунология, 2014 . Chronical course of infection caused by hepatitis C virus is accompanied by increase Fas-positive lymphocytes of peripheral blood. Cultivation of agglutinin-stimulated mononuclear blood cells of patients with chronic hepatitis C revealed inhibition of ...
V. V. Novitsky +8 more
doaj +1 more source
Advanced Science, EarlyView.ABSTRACT Precise transgene‐free gene upregulation remains a challenge in crop biotechnology, as conventional enhancers often exceed CRISPR‐mediated knock‐in size constraints and face regulatory hurdles. Here we establish a foundational cross‐species resource of compact transcriptional enhancers developed via STEM‐seq, a high‐throughput screening ...
Qi Yao +14 more
wiley +1 more source