Harvesting AAV by tangential flow filtration using reverse asymmetric membranes
Abstract Efficient bioreactor clarification for harvesting virus particles is often challenging. Tangential flow filtration is attractive as it can be easily adapted for batch and perfusion operations. Here the feasibility of using reverse asymmetric hollow fiber membranes, where the more open support structure faces the feed stream, has been ...
Xiaolei Hao+5 more
wiley +1 more source
Abstract Biopharmaceutical manufacturing processes in which the product of interest is extracellularly expressed typically employ a clarification step following cell culture or fermentation. During clarification, crude cell culture fluid or fermentation broth is processed to remove insoluble solids, cells, debris, and other particulates, with the ...
Kyeong‐won Yeop+7 more
wiley +1 more source
In vitro culture of porcine respiratory nasal mucosa explants for studying the interaction of orcine viruses with the respiratory tract [PDF]
Favoreel, Herman+5 more
core
Insect-proof netting technique: Effective control of Bemisia tabaci and Tomato chlorosis virus (ToCV) in protected cultivations in China [PDF]
Fan Wang+6 more
openalex +1 more source
Abstract Background Colorectal cancer liver metastasis (CRLM) is characterized by an immunosuppressive microenvironment and a blunted response to immunotherapy. Notably, tumor‐associated macrophages (TAMs) play a critical role in modulating immune responses and exhibit significant heterogeneity in CRLM.
Yizhi Zhan+11 more
wiley +1 more source
High Cell Density Perfusion Process of Quail Cells Producing Oncolytic rVSV-NDV. [PDF]
Jacobtorweihe L+5 more
europepmc +1 more source
Consumer Behaviour in the Metaverse: Empirical Insights From a Meta‐Analysis
ABSTRACT Metaverses are rapidly expanding, yet the complexities inherent in these virtual environments remain insufficiently understood, which, in turn, limits the ability to anticipate potential challenges and capitalize on emerging opportunities.
Wagner Junior Ladeira+5 more
wiley +1 more source
Eugenia brasiliensis: Analysis of the Chemical Profile and Evaluation of Cytotoxic Potential
Leaves of Eugenia brasiliensis were dried, crushed and macerated with polarity increment. The antiporliferative and anti‐migratory potential and the cell cycle were evaluated. 28 compounds were tentatively identified by mass sceptrometry. ABSTRACT This work evaluated the antiproliferative potential of Eugenia brasiliensis leaf extracts against the HeLa
Giovana G. F. V. de Oliveira+9 more
wiley +1 more source
Coexistence of human pegivirus infection and poor hematopoietic reconstruction in a lymphoma patient after autologous hematopoietic stem cell transplantation: A case report and literature review. [PDF]
Kang J+7 more
europepmc +1 more source