Results 191 to 200 of about 134,248 (355)

Harvesting AAV by tangential flow filtration using reverse asymmetric membranes

open access: yesBiotechnology Progress, EarlyView.
Abstract Efficient bioreactor clarification for harvesting virus particles is often challenging. Tangential flow filtration is attractive as it can be easily adapted for batch and perfusion operations. Here the feasibility of using reverse asymmetric hollow fiber membranes, where the more open support structure faces the feed stream, has been ...
Xiaolei Hao   +5 more
wiley   +1 more source

Optimizing clarification processes in biopharmaceutical manufacturing through quality by design: Strategies, implications, and future prospects

open access: yesBiotechnology Progress, EarlyView.
Abstract Biopharmaceutical manufacturing processes in which the product of interest is extracellularly expressed typically employ a clarification step following cell culture or fermentation. During clarification, crude cell culture fluid or fermentation broth is processed to remove insoluble solids, cells, debris, and other particulates, with the ...
Kyeong‐won Yeop   +7 more
wiley   +1 more source

In vitro culture of porcine respiratory nasal mucosa explants for studying the interaction of orcine viruses with the respiratory tract [PDF]

open access: yes, 2007
Favoreel, Herman   +5 more
core  

Targeting SPHK1 in macrophages remodels the tumor microenvironment and enhances anti‐PD‐1 immunotherapy efficacy in colorectal cancer liver metastasis

open access: yesCancer Communications, EarlyView.
Abstract Background Colorectal cancer liver metastasis (CRLM) is characterized by an immunosuppressive microenvironment and a blunted response to immunotherapy. Notably, tumor‐associated macrophages (TAMs) play a critical role in modulating immune responses and exhibit significant heterogeneity in CRLM.
Yizhi Zhan   +11 more
wiley   +1 more source

High Cell Density Perfusion Process of Quail Cells Producing Oncolytic rVSV-NDV. [PDF]

open access: yesEng Life Sci
Jacobtorweihe L   +5 more
europepmc   +1 more source

Consumer Behaviour in the Metaverse: Empirical Insights From a Meta‐Analysis

open access: yesJournal of Consumer Behaviour, EarlyView.
ABSTRACT Metaverses are rapidly expanding, yet the complexities inherent in these virtual environments remain insufficiently understood, which, in turn, limits the ability to anticipate potential challenges and capitalize on emerging opportunities.
Wagner Junior Ladeira   +5 more
wiley   +1 more source

Eugenia brasiliensis: Analysis of the Chemical Profile and Evaluation of Cytotoxic Potential

open access: yesChemistry &Biodiversity, EarlyView.
Leaves of Eugenia brasiliensis were dried, crushed and macerated with polarity increment. The antiporliferative and anti‐migratory potential and the cell cycle were evaluated. 28 compounds were tentatively identified by mass sceptrometry. ABSTRACT This work evaluated the antiproliferative potential of Eugenia brasiliensis leaf extracts against the HeLa
Giovana G. F. V. de Oliveira   +9 more
wiley   +1 more source

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