Results 181 to 190 of about 4,994 (256)

Novel Organelle‐Based Intracellular Immunity With Mechanistic and Therapeutic Implications

Barrier Immunity, EarlyView.
A conceptual framework illustrating how PAMPs/DAMPs initiate barrier, innate, adaptive, and intracellular immune responses, with organelle‐based intracellular immunity serving as a central integrator linking metabolism, inflammatory signaling, and therapeutic interventions to restore immune homeostasis.
Keman Xu, Shih‐Yu Hung, Fatma Saaoud, Ying Shao, Yifan Lu, Juanjuan Liu, Bo Yuan, Haiyan Xiang, Hong Wang, Xiaofeng Yang   +9 more
wiley   +1 more source

Expression of mutant TIE2 p.L914F during mouse development causes embryonic lethality and defects in vascular remodeling

Developmental Dynamics, EarlyView.
Abstract Background Sporadic venous malformation (VM) is associated with the hyperactivating p.L914F mutation in TIE2, a receptor tyrosine kinase essential for vascular development. This mutation is not found in hereditary VM, suggesting incompatibility with life when expressed during early vascular development.
Lindsay J. Bischoff, Sandra Schrenk, Kara Soroko, Chhiring Sherpa, Ashok Arasu, Damien Reynaud, Elisa Boscolo   +6 more
wiley   +1 more source

Estudio de prevalencia: Virus de la Hepatitis B en la provincia de Valencia

, 2020
Hepatitis B is a viral disease and one of the most important causes in the development of liver disease. In 2016, WHO published its strategy with the aim of eliminating viral hepatitis, a threat to public health by 2030. The objective is to analyze the evolution of chronic hepatitis B in the health area of the General Hospital between 2019-2020. Define
openaire   +1 more source

Comportamiento de la regeneración hepática humana en infecciones por virus hepatitis B y C

The liver is an organ that normally regenerates after acute liver injury, while responding with fibrosis in chronic liver injury. In the case of a viral infection, activation of pathways that fatten the hepatocyte initiates a regeneration response.
Vergara-Dagobeth, Edgar, Vergara-García, Oscar, Pajaro-Castro, Nerlis   +2 more
core   +1 more source

Transendocardial injection of expanded autologous CD34+ cells after myocardial infarction: Design of the EXCELLENT trial

ESC Heart Failure, Volume 12, Issue 2, Page 1455-1463, April 2025.
Abstract Aims The extent of irreversible cardiomyocyte necrosis after acute myocardial infarction (AMI) is a major determinant of residual left ventricular (LV) function and clinical outcome. Cell therapy based on CD34+ cells has emerged as an option to help repair the myocardium and to improve outcomes.
Jerome Roncalli, François Roubille, Nicolas Meyer, Giulio Pompilio, Lionel Leroux, Philippe Henon, Guillaume Trebuchet, Anthony Criquet, Matthieu de Kalbermatten, Eric Saloux, Alain Manrique, Pierre‐Yves Marie, Deepak L. Bhatt, Scott D. Solomon, Gilles Montalescot, David E. Newby, Faiez Zannad, on behalf of the EXCELLENT Trial Investigators   +17 more
wiley   +1 more source

Vacinação contra Hepatite B em indivíduos renais crônicos em tratamento hemodialítico [Hepatitis B vaccination in chronic renal failure patients on hemodialysis]

Revista Enfermagem UERJ, 2014
Indivíduos em tratamento hemodialítico apresentam elevado risco de infecção pelo Vírus da Hepatite B, sendo, portanto, uma população alvo para vacinação contra Hepatite B.
Letícia Pimenta Lopes, Sheila Araujo Teles, Elen Almeida Romão, Silmara Elaine Malaguti Toffano, Deborah Ferreira Noronha de Castro Rocha, Elucir Gir   +5 more
doaj  

Reactivación del virus de la hepatitis B secundaria a tratamiento inmunosupresor

, 2011
Se presenta el caso de una mujer de 57 años con síntomas dispépticos, con ANAS +, manejada con terapia inmunosupresora y sospecha clínica de LES. Posteriormente presenta ascitis y elevación de las aminotransferasas. Se detecta HBsAg + con carga viral DNA-HBV elevada.
Huertas Gamboa, José Fernando, Hurtado H, Jean Sebastián, Holguín Rojas, Jaime   +2 more
openaire   +1 more source

Development of Pentaplex Reverse Transcription Droplet Digital PCR Assay for Simultaneous Detection and Absolute Quantification of HIV‐1, HIV‐2, HCV, and HBV With Internal Control

ELECTROPHORESIS, EarlyView.
Development of Pentaplex reverse transcription droplet digital PCR assay for simultaneous detection and absolute quantification of HIV‐1, HIV‐2, HCV, and HBV with internal control. The channel‐resolved multiplex strategy enables high sensitivity, robust quantification, and scalable digital PCR workflows across platforms.
Soo Yeon Lim, Un Na Koh, Ah Leum Kim, Yebin Kim, Ga Eun Kim, Si‐Keun Lim   +5 more
wiley   +1 more source

Resistencia a la terapia antiviral del virus de hepatitis B

, 2011
El virus hepatitis B (HBV) es responsable de una elevada morbimortalidad de distribución mundial. Las consecuencias clínicas de las infecciones por este virus (hepatitis crónica, cirrosis, hepatocarcinoma) dependen tanto de factores relacionados inherentes al hospedador como al agente viral.
openaire   +1 more source

High‐frequency oscillations after acute hemorrhagic traumatic brain injury: insights into posttraumatic epilepsy development

Epilepsia, EarlyView.
Abstract Objective The development of posttraumatic epilepsy after traumatic brain injury (TBI) is potentially identifiable by measuring biomarkers of epileptogenesis, namely pathological high‐frequency oscillations (pHFOs). pHFOs are promising candidates, but it remains uncertain whether they can be detected early after TBI in clinical settings.
Kseniia Kriukova, Lin Li, Richard J. Staba, Misque Boswell, Tuba Asifriyaz, Rachel Thomas, James J. Gugger, Mohamad Shamas, Ramon Diaz‐Arrastia, Manuel Buitrago Blanco, Jerome Engel, Paul M. Vespa, Dominique Duncan, on behalf of the EpiBios4Rx investigators, Denes Agoston, Alicia K. Au, Michael Bell, Ben Churn, Jan Claassen, Ramon Diaz‐Arrastia, Jerome Engel, Brandon Foreman, Aristea Galanopoulou, Emily Gilmore, Martin Hunn, Nathalie Jette, Andrew Morokoff, Solomon L. Moshé, Terence O'Brien, Joshua Laing, Piero Perucca, Kristine H. O'Phelan, Asla Pitkanen, Eric Rosenthal, Frederick Willyerd, Lara Zimmermann, Ben Ellingson, Buitrago Blanco, Daniel Correa, Dana Harrar, Thomas P. Bleck, Brian Appavu, Aaron Struck, Baxter Allen, Inna Keselman, Jeff Kennedy, Victor Ferastraoaru, Ji Yeoun Yoo, Arthur W. Toga   +48 more
wiley   +1 more source