Results 101 to 110 of about 43,898 (301)

p300 Degradation by the p53‐SIAH1 Axis Relieves TBK1 Acetylation to Enhance Innate Antiviral Immunity

open access: yesAdvanced Science, EarlyView.
This study identifies p300 as the acetyltransferase that acetylates TBK1 and inhibits its phosphorylation. Activation of the p53‐SIAH1 axis by immune response downregulates p300 expression to sustain innate antiviral immunity. Conditional p300 knockout in alveolar epithelial cells in vivo promotes antiviral responses and suppresses virus replication ...
Huidi Yu   +6 more
wiley   +1 more source

Macrophage‐derived MLKL in alcohol‐associated liver disease: Regulation of phagocytosis

open access: yesHepatology, EarlyView., 2022
EtOH causes leaky gut allowing bacteria and PAMPs into the liver, resulting in hepatic inflammation and injury. We demonstrate that LPS induces STAT1‐mediated expression and phosphorylation of MLKL in macrophages and identify a novel function that myeloid MLKL translocates to phagosomes and lysosomes and regulates phagocytosis, which contributes to the
Xiaoqin Wu   +16 more
wiley   +1 more source

Prevalencia del virus de la hepatitis C en las unidades de hemodiálisis de la región occidental cubana Hepatitis C virus present in hemodialysis units from Cuban western region

open access: yesRevista Cubana de Medicina, 2009
La población de hemodiálisis constituye un grupo de alto riesgo en el caso de la infección por el virus de la hepatitis C. Se realizó un análisis multicéntrico de la prevalencia de la infección por el virus de la hepatitis C en las unidades de diálisis ...
Rita Rosa Santana Hernández   +3 more
doaj  

Development of multiple myeloma in a patient with chronic hepatitis C: A case report and review of the literature

open access: yes, 2006
An association between chronic hepatitis C virus (HCV) infection and essential mixed cryoglobulinaemia and non-Hodgkin lymphoma (NHL) has been suggested. However, a causative role of HCV in these conditions has not been established.
Lakatos, Péter László   +4 more
core  

The Spectrum of Biopsy‐Proven Renal Diseases in Chinese Elderly Patients and Its Temporal Shift Over 20 Years: A Retrospective Cohort Study

open access: yesAGING MEDICINE, EarlyView.
This 20‐year retrospective study reveals a significant increase in renal biopsy utilization and a pivotal shift in biopsy‐proven renal disease among Chinese elderly patients. Secondary glomerular nephropathy (particularly diabetic nephropathy and hypertensive nephropathy) has surpassed primary glomerular nephropathy as the leading biopsy‐proven ...
Shasha Han   +4 more
wiley   +1 more source

Circulating TREM2 as a noninvasive diagnostic biomarker for NASH in patients with elevated liver stiffness

open access: yesHepatology, EarlyView., 2022
Abstract Background and Aims Reliable noninvasive biomarkers are an unmet clinical need for the diagnosis of NASH. This study investigates the diagnostic accuracy of the circulating triggering receptor expressed on myeloid cells 2 (plasma TREM2) as a biomarker for NASH in patients with NAFLD and elevated liver stiffness.
Vineesh Indira Chandran   +17 more
wiley   +1 more source

Manifestaciones cutáneas de la hepatitis C

open access: yesMedimay, 2010
El virus de la hepatitis C, es una causa muy importante de hepatitis tanto aguda como crónica y es un gran problema de salud, ya que puede evolucionar a la cirrosis y al carcinoma hepatocelular.
Doraiquis Lázara Acosta Medina   +3 more
doaj   +4 more sources

Diagnóstico diferencial de virus hepatótropos y no hepatótropos en pacientes atendidos en el Laboratorio Regional de Referencia Virológica. Maracaibo-Venezuela, año 2007

open access: yesKasmera, 2010
: Viral hepatitis is a public health problem worldwide, caused by different etiologic agents, such as hepatitis A, B, C, D, E, F or G. However, cases have been reported related to liver disease caused by hepatotropic viruses, such as cytomegalovirus (CMV)
Costa-León Luciana   +6 more
doaj  

Epidemiology of hepatitis virus in the Colombian Amazon after 15 years of hepatitis B vaccination.

open access: yes, 2010
Hepatitis B virus infection (HBV) is an endemic public health problem in many countries around the globe. Latin America (LA) is considered an area of low and medium endemicity for hepatitis B infection. A highly effective vaccine has been available since
De la Hoz Restrepo, Fernando
core  

Hepatitis B Virus Infection Among Antenatal Clinic Attendees at the Muhimbili National Hospital, Seroprevalence and Associated Factors [PDF]

open access: yes, 2011
Hepatitis B virus (HBV) infection is a serious public health problem in sub-Saharan Africa. Vertical transmission is one of the modes of transmission. The risk of transmission increases if the mother is hepatitis B surface antigen (HBsAg) positive and ...
Rashid, Sabria
core  

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