Results 21 to 30 of about 153,175,670 (281)

Combinación de ledipasvir/sofosbuvir como tratamiento de la infección crónica por hepatitis C

Anales de Pediatría, 2019
Resumen: Introducción: El objetivo del estudio fue evaluar la seguridad y la eficacia de la combinación de ledipasvir/sofosbuvir en la infección crónica por el genotipo 1 y 4 del virus de la hepatitis C (VHC) en pacientes pediátricos.
Jesús Quintero, Javier Juampérez, Ecaterina Julio, Vanessa Cabello, Maria Mercadal-Hally, Pere Soler-Palacín, Óscar Segarra, Carlos Rodrigo   +7 more
doaj   +1 more source

Cost-effective analysis of different algorithms for the diagnosis of hepatitis C virus infection.

Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 2008
We compared the cost-benefit of two algorithms, recently proposed by the Centers for Disease Control and Prevention, USA, with the conventional one, the most appropriate for the diagnosis of hepatitis C virus (HCV) infection in the Brazilian population ...
A. M. Barreto, K. Takei, Sabino E. C., M. A. O. Bellesa, N. Salles, C. Barreto, A. Nishiya, D. Chamone   +7 more
semanticscholar   +1 more source

Hepatitis C crónica: aspectos clínicos, serológicos y de tratamiento en dos centros de atención en Bogotá, Colombia

Revista Colombiana de Gastroenterología, 2014
Introducción: el virus de la hepatitis C afecta a cerca de 170 millones de personas en el mundo. La organización mundial de la salud (OMS) estima una prevalencia mundial del 2%.
Jhon Edison Prieto Ortíz, Santiago Sánchez Pardo, Ever Leonardo Rojas Díaz, Sandra Judith Huertas Pacheco   +3 more
doaj   +1 more source

Ledipasvir/sofosbuvir combination for chronic hepatitis C infection in children and adolescents

Anales de Pediatría (English Edition), 2019
Introduction: The aim of this study was to assess the safety and efficacy of ledipasvir/sofosbuvir combination in chronic Hepatitis C Virus (HCV) genotype 1 and 4 infection in paediatric patients.
Jesús Quintero, Javier Juampérez, Ecaterina Julio, Vanessa Cabello, Maria Mercadal-Hally, Pere Soler-Palacín, Óscar Segarra, Carlos Rodrigo   +7 more
doaj   +1 more source

The Novel Nucleoside Analog R1479 (4′-Azidocytidine) Is a Potent Inhibitor of NS5B-dependent RNA Synthesis and Hepatitis C Virus Replication in Cell Culture*

Journal of Biological Chemistry, 2006
Hepatitis C virus (HCV) polymerase activity is essential for HCV replication. Targeted screening of nucleoside analogs identified R1479 (4′-azidocytidine) as a specific inhibitor of HCV replication in the HCV subgenomic replicon system (IC50 = 1.28 μm ...
K. Klumpp, V. Leveque, S. Le Pogam, Han Ma, Wenjing Jiang, Hyunsoon Kang, C. Granycome, M. Singer, C. Laxton, J. Hang, K. Sarma, D. Smith, D. Heindl, C. J. Hobbs, J. H. Merrett, J. Symons, N. Cammack, J. A. Martin, R. de Vos, I. Nájera   +19 more
semanticscholar   +1 more source

Seroprevalence of hepatitis A virus, hepatitis B virus, hepatitis C virus, and syphilis among human immunodeficiency virus-infected people at a university hospital, Turkey

, 2020
Introduction Infections such as viral hepatitis and syphilis that share similar transmission routes with human immunodeficiency virus (HIV) may adversely affect the course of the disease.
Heval Can Bilek, Aydın Deveci, Esra Aksakal Tanyel   +2 more
core   +1 more source

Beyond Members of the Flaviviridae Family, Sofosbuvir Also Inhibits Chikungunya Virus Replication

Antimicrobial Agents and Chemotherapy, 2018
Chikungunya virus (CHIKV) causes a febrile disease associated with chronic arthralgia, which may progress to neurological impairment. Chikungunya fever (CF) is an ongoing public health problem in tropical and subtropical regions of the world, where ...
André C. Ferreira, P. Reis, C. S. de Freitas, C. Sacramento, Lucas Villas Bôas Hoelz, M. Bastos, Mayara Mattos, Natasha Rocha, Isaclaudia Gomes de Azevedo-Quintanilha, Gouveia Pedrosa Carolina da Silva, Leticia Rocha Quintino Souza, Erick Correia Loiola, P. Trindade, Yasmine Rangel Vieira, G. Barbosa-Lima, H. C. de Castro Faria, N. Boechat, S. Rehen, K. Brüning, F. Bozza, P. Bozza, T. Souza   +21 more
semanticscholar   +1 more source

Human Immunodeficiency Virus/Hepatits C Virus Coinfection in Spain: Elimination Is Feasible, but the Burden of Residual Cirrhosis Will Be Significant

Open Forum Infectious Diseases, 2018
Background We assessed the prevalence of antibodies against hepatitis C virus (HCV-Abs) and active HCV infection in patients infected with human immunodeficiency virus (HIV) in Spain in 2016 and compared the results with those of similar studies ...
J. Berenguer, I. Jarrín, L. Pérez-Latorre, V. Hontañón, M. Vivancos, J. Navarro, M. J. Téllez, J. Guardiola, J. Iribarren, A. Rivero-Juarez, M. Márquez, A. Artero, L. Morano, I. Santos, J. Moreno, M. Fariñas, M. Galindo, M. A. Hernando, M. Montero, C. Cifuentes, P. Domingo, J. Sanz, Lourdes Domíngez, O. Ferrero, B. de la Fuente, C. Rodríguez, S. Reus, J. Hernández-Quero, G. Gaspar, L. Perez-Martinez, C. García, L. Force, S. Veloso, J. Losa, J. Vilaró, E. Bernal, S. Arponen, A. Orti, Á. Chocarro, R. Teira, G. Alonso, R. Silvariño, A. Vegas, P. Geijo, J. Bisbe, H. Esteban, J. González-García   +46 more
semanticscholar   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Urinary porphyrin excretion in hepatitis C infection [PDF]

, 1999
A high prevalence of hepatitis C virus infection in porphyria cutanea tarda in some populations suggests a close link between viral hepatitis and alteration of porphyrin metabolism.
Jacob, Karl, Vogeser, Michael, Zachoval, Reinhart   +2 more
core   +1 more source