Results 71 to 80 of about 153,175,670 (281)

Hepatitis C Treatment: A Community-Based, Multidisciplinary Approach to Increase Access and Improve Health Perceptions [PDF]

, 2012
Hepatitis C is a major international health care dilemma, occurring frequently in populations who suffer from other health care disparities. Hepatitis C is the most common blood-borne infection and the leading cause of liver disease in the United States (
Leigh, Elaine A.
core  

Inducible nitric oxide synthase gene (NOS2A) haplotypes and the outcome of hepatitis C virus infection.

, 2004
Inducible nitric oxide synthase (iNOS) is an important molecule involved in the host defense against infectious agents. iNOS is encoded by the NOS2A gene and well-defined haplotypes exist with respect to this gene.
Hennig, BJW, Knapp, S, Burgner, D, Hill, AVS, Yee, LJ, Thomas, HC, Frodsham, A J, Thursz, MR, Thomas, H C, Hill, A V S, Frodsham, AJ, Thursz, M R, Hennig, B J W, Yee, L J, Wright, M   +14 more
core   +1 more source

Rab1A Promotes Hepatic Steatosis by Suppressing Mitophagy via the Raf‐1/ERK1/2/PINK1 Signaling Axis

Advanced Science, EarlyView.
Why does fat accumulate in the liver? Our study reveals Rab1A as the molecular switch that silences the cell's mitochondrial cleanup crew. Turning Rab1A off reactivates mitophagy, clears excess fat, and reverses fatty liver disease in mice—offering a promising new therapeutic target for MASLD, a growing global health challenge.
Li Zhang, Jianhua Li, Huilu Zhang, Qi Qin, Yichen Huang, Xiaofan Tian, Chao Sun, Binbin Li, Zhengxin Wang, Xin Zhang   +9 more
wiley   +1 more source

Incidencia de infección por el virus de la hepatitis B y C

Revista Cubana de Medicina, 2001
Se sabe que los pacientes con tumores malignos y tratamiento con citostáticos se encuentran expuestos a sufrir infecciones virales por el uso frecuente de la vía parenteral.
Elia Neninger Vinageras, Pedro Velbes Marquetti, Concepción del Castillo Carrillo   +2 more
doaj  

Association between physical activity and risk of hepatobiliary cancers: A multinational cohort study.

Journal of Hepatology, 2019
BACKGROUND & AIMS To date, evidence on the association between physical activity and risk of hepatobiliary cancers has been inconclusive. We examined this association in the European Prospective Investigation into Cancer and Nutrition cohort (EPIC ...
S. Baumeister, Sabrina Schlesinger, K. Aleksandrova, C. Jochem, M. Jenab, M. Gunter, K. Overvad, A. Tjønneland, M. Boutron-Ruault, F. Carbonnel, Agnès Fournier, T. Kühn, R. Kaaks, T. Pischon, H. Boeing, A. Trichopoulou, C. Bamia, C. la Vecchia, Giovanna Masala, S. Panico, F. Fasanelli, R. Tumino, S. Grioni, B. Bueno-de-Mesquita, R. Vermeulen, A. May, K. Borch, S. O. Oyeyemi, E. Ardanaz, M. Rodríguez-Barranco, María Dolores Chirlaque López, M. Felez-Nobrega, E. Sonestedt, Bodil Ohlsson, O. Hemmingsson, M. Werner, A. Perez-Cornago, Pietro Ferrari, M. Stępień, H. Freisling, K. Tsilidis, H. Ward, E. Riboli, E. Weiderpass, Michael F. Leitzmann   +44 more
semanticscholar   +1 more source

Engineering Microbial Particles for Next‐Generation Biomedical Platforms

Advanced Science, EarlyView.
Microbe‐derived particles (MDPs), which include extracellular vesicles, outer membrane vesicles, inclusion bodies, polysaccharide particles, and virus‐like particles, represent a rapidly expanding category of bioinspired nanomaterials. With their natural origin, intrinsic biocompatibility, and highly programmable functionality, MDPs serve as a ...
Yuting Li, Yunjie Lu, Ziyan Huang, Jianjiang Chen, Yanbin Liu, Lei Qin, Chao Wang, Yumin Wu   +7 more
wiley   +1 more source

Molecular basis of telaprevir resistance due to V36 and T54 mutations in the NS3-4A protease of the hepatitis C virus [PDF]

, 2008
Background The inhibitor telaprevir (VX-950) of the hepatitis C virus (HCV) protease NS3-4A has been tested in a recent phase 1b clinical trial in patients infected with HCV genotype 1. This trial revealed residue mutations that confer varying degrees of
Stefan Zeuzem, Albrecht, M., Hartmann, Christoph, Mayr, G., Andreas Schlicker, Welsch, C., Sarrazin, C., Susser, Simone, Sarrazin, Christoph, Lengauer, T., Albrecht, Mario, Christoph Welsch, Thomas Lengauer, Christoph Sarrazin, Antes, I., Mayr, Gabriele, Iris Antes, Simone Susser, Gabriele Mayr, Lengauer, Thomas, Susser, S., Zeuzem, S., Hartmann, C., Christoph Hartmann, Mario Albrecht, Schlicker, A., Francisco S Domingues, Domingues, Francisco S., Domingues, F., Welsch, Christoph, Schlicker, Andreas, Antes, Iris, Zeuzem, Stefan, Welsch, C.;Domingues, F. S.;Susser, S.;Antes, I.;Hartmann, C.;Mayr, G.;Schlicker, A.;Sarrazin, C.;Albrecht, M.;Zeuzem, S.;Lengauer, T.   +33 more
core   +1 more source

Hepatitis C: una aproximación clínica y epidemiológica en Cali, Colombia

Revista Colombiana de Gastroenterología, 2018
Introducción: en Colombia, la infección por el virus de la hepatitis C (VHC) representa alta morbilidad y elevados costos. Con la llegada de nuevos tratamientos más efectivos, se hace necesario conocer las características propias de esta población para ...
Carlos Arturo Rojas Rodríguez, Angelica Tobon Guevara, Mauricio Sepulveda Copete, Nelson Rojas Rojas, Diego Fernando Jimenez Rivera   +4 more
doaj  

SEQUENCE SIMILARITY BETWEEN THYROID SELF-PROTEIN AND HEPATITIS C VIRUS POLYPROTEIN: possible triggering mechanism of autoimmune thyroiditis.

Arquivos de Gastroenterologia, 2016
BACKGROUND - Exposure to viral antigens that share amino acid sequence similar with self- antigens might trigger autoimmune diseases in genetically predisposed individuals, and the molecular mimicry theory suggests that epitope mimicry between the virus ...
Maristella de Araújo Carvalho Sousa, R. Paraná, L. J. de Oliveira Andrade   +2 more
semanticscholar   +1 more source

Gestational Hypoxia Disrupts Medial Ganglionic Eminence Progenitor Dynamics and Interneuron Development in Schizophrenia

Advanced Science, EarlyView.
FES‐derived MGE spheroids exhibit progenitor‐stage alterations in developmental trajectory and hypoxia‐responsive transcriptional programs, followed by functional disruption. Gestational hypoxia recapitulates impaired progenitor proliferation, shortened cell‐cycle progression, interneuron developmental abnormalities, and schizophrenia‐like behaviors in
Peiyan Ni, Qiancheng Zhang, Youhui Jiang, Huiying Yao, Chuqing Zhou, Xiaoyi Tian, Shiyingnan Gao, Jun Zhao, Xinyi Ren, Naxin Xu, Mengshan Fu, Liansheng Zhao, Xueyu Qi, Xueli Yu, Wanjun Guo, Sangmi Chung, Fan Guo, Tao Li   +17 more
wiley   +1 more source