Results 141 to 150 of about 1,115,168 (306)

Histological Evidence of Pulmonary Microthrombosis and Vasculitis in Life-Threatening Respiratory Virus Diseases. [PDF]

Open Forum Infect Dis, 2021
Dolby HW, Potey P, Wilder-Smith AB, Clohisey S, Millar JE, Baillie JK, Dorward DA, Lucas CD, Russell CD.   +8 more
europepmc   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

Evaluation of protective efficacy of an inactivated Japanese encephalitis virus genotype Ⅴ strain in mice

npj Vaccines
The detection of Japanese encephalitis virus (JEV) genotype V (GV) in humans in Korea in 2015 has raised concerns regarding its potential public health impact.
Jung-Min Lee, Seong-Ryeol Kim, Jungsang Ryou, Jang-Hoon Choi, Sang-Mu Shim   +4 more
doaj   +1 more source

Virus Diseases [PDF]

BMJ, 1939
openaire   +2 more sources

Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound

FEBS Open Bio, EarlyView.
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda, Natsue Maezono, Rina Uchikoshi, Nobuyuki Kato, Masanori Ikeda   +4 more
wiley   +1 more source

Chemotherapy in Virus Diseases [PDF]

BMJ, 1947
openaire   +2 more sources

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source

Viral hemorrhagic fevers, Junin virus, Lassa virus, Lujo virus: (Week 49) Weekly cases* of notifiable diseases, United States, U.S. territories, and Non-U.S. Residents week ending December 11, 2021 [PDF]

This data includes weekly cases of notifiable diseases, United States, U.S. Territories, and Non-U.S. Residents, specifically covering Viral hemorrhagic fevers; Junin virus, Lassa virus, Lujo virus cases.

core   +2 more sources

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Temporal evolution of insecticide resistance and bionomics in Anopheles funestus, a key malaria vector in Uganda

Scientific Reports
Insecticide resistance escalation is decreasing the efficacy of vector control tools. Monitoring vector resistance is paramount in order to understand its evolution and devise effective counter-solutions.
Ambrose Oruni, Magellan Tchouakui, Carlos S. Djoko Tagne, Jack Hearn, Jonathan Kayondo, Charles S. Wondji   +5 more
doaj   +1 more source