Results 171 to 180 of about 1,749,390 (349)

Viral Entry through CXCR4 Is a Pathogenic Factor and Therapeutic Target in Human Immunodeficiency Virus Type 1 Disease

, 2000
Birgit Schramm, Michael L. Penn, Roberto F. Speck, Stephen Y. Chan, Erik De Clercq, Dominique Schols, Ruth I. Connor, Mark A. Goldsmith   +7 more
openalex   +2 more sources

Foot-and-Mouth Disease Virus Nonstructural Protein 2C Interacts with Beclin1, Modulating Virus Replication [PDF]

, 2012
Douglas P. Gladue, Vivian O’Donnell, R. Baker-Branstetter, Lauren G. Holinka, Juan M. Pacheco, I. Fernández-Sainz, Zhiqiang Lu, Emiliana Brocchi, Barry Baxt, M E Piccone, Luis L. Rodrı́guez, Manuel V. Borca   +11 more
openalex   +1 more source

CX3CL1 in Early Detection of Alzheimer's Disease: Plasma Dynamics Across Age and Disease Stages

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Backgrounds Alzheimer's disease (AD) is characterized by amyloid‐beta plaques, tau tangles, and neuroinflammation. C‐X3‐C motif chemokine ligand 1 (CX3CL1, also known as fractalkine), a neuroimmune chemokine implicated in AD pathogenesis, shows inconsistent alterations in plasma/serum across studies.
Ling Wang, Yujie Liu, Fei Li, Xuelin Li, Lanlan Li, Jie Zhang, Yali Xu   +6 more
wiley   +1 more source

Complete Genome Sequences of Newcastle Disease Virus Strains Circulating in Chicken Populations of Indonesia [PDF]

, 2012
Sa Xiao, Anandan Paldurai, Baibaswata Nayak, Arthur Samuel, Eny E. Bharoto, Teguh Y. Prajitno, Peter L. Collins, Siba K. Samal   +7 more
openalex   +1 more source

Pharmacokinetics, Pharmacodynamics, and Safety of Subcutaneous Belimumab in Pediatric Patients with Systemic Lupus Erythematosus: A Multicenter, Open‐Label Trial

Arthritis Care &Research, Accepted Article.
Objective This study aimed to characterize the pharmacokinetics, pharmacodynamics, safety, and exploratory efficacy of subcutaneous belimumab in pediatric patients with active systemic lupus erythematosus (SLE) receiving standard therapy. Methods This single‐arm, multicenter, open‐label trial (GSK study 200908; NCT04179032) used three‐weight‐band ...
Hermine I. Brunner, Jordi Antón, Inmaculada Calvo‐Penadés, Richard Dimelow, Gerd Horneff, Sylvia Kamphuis, Rebecca Marino, Andre van Maurik, Kirsten Minden, Masaaki Mori, Josephine Ocran‐Appiah, Christel Wilkinson, Yuichi Yamasaki, Deepak Assudani, for the Pediatric Rheumatology Collaborative Study Group (PRCSG) and Paediatric Rheumatology International Trials Organisation (PRINTO) network investigators   +14 more
wiley   +1 more source

Veterinary Diagnostic Approach of Common Virus Diseases in Adult Honeybees. [PDF]

Vet Sci, 2020
Dittes J, Aupperle-Lellbach H, Schäfer MO, Mülling CKW, Emmerich IU.   +4 more
europepmc   +1 more source

Thymic Function Failure Is Associated With Human Immunodeficiency Virus Disease Progression [PDF]

, 2017
Sara Ferrando‐Martínez, Rebeca S. De Pablo-Bernal, M. De Luna-Romero, Santiago Jiménez de Ory, Miguel Genebat, Yolanda M. Pacheco, F Parras, Marta Montero, José Ramón Blanco, Félix Gutiérrez, Jesús Santos, Francisco Vidal, Richard A. Koup, María Ángeles Muñoz‐Fernández, Manuel Leal, Ezequiel Ruíz-Mateos   +15 more
openalex   +1 more source

Evaluation of the ebola virus disease preparedness and readiness program in Uganda: 2018 to 2019

, 2021
Peter Nsubuga, Ben Masiira, Christine Kihembo, Jayne Byakika-Tusiime, Caroline Ryan, Miriam Nanyunja, Raoul Kamadjeu, Ambrose Talisuna   +7 more
openalex   +1 more source

Lipid Nanoparticles for the Delivery of CRISPR/Cas9 Machinery to Enable Site‐Specific Integration of CFTR and Mutation‐Agnostic Disease Rescue

Advanced Functional Materials, EarlyView.
Lipid nanoparticles (LNPs) are optimized to co‐deliver Cas9‐encoding messenger RNA (mRNA), a single guide RNA (sgRNA) targeting the endogenous cystic fibrosis transmembrane conductance regulator (CFTR) gene, and homologous linear double‐stranded donor DNA (ldsDNA) templates encoding CFTR.
Ruth A. Foley, Paul G. Ayoub, Vrishti Sinha, Colin Juett, Alicia Sanoyca, Emily C. Duggan, Lindsay E. Lathrop, Priyanka Bhatt, Kevin Coote, Beate Illek, Brigitte N. Gomperts, Donald B. Kohn, Steven J. Jonas   +12 more
wiley   +1 more source

Replication of Marek's Disease Virus Is Dependent on Synthesis of De Novo Fatty Acid and Prostaglandin E ₂ [PDF]

, 2019
Nitish Boodhoo, Nitin Machindra Kamble, Benedikt B. Kaufer, Shahriar Behboudi   +3 more
openalex   +1 more source