Advanced Functional Materials, EarlyView.FeDSNP‐Pa, a metallized nanoparticle loaded with sodium pyruvate (Pa), exerts triple therapeutic effects by scavenging reactive oxygen species (ROS), suppressing inflammatory responses, and inhibiting pyroptosis signaling pathways. This multifunctional neuroprotective strategy protecting retinal ganglion cells (RGCs) from elevated intraocular pressure ...
Yukun Wu +5 more
wiley +1 more source
Antiviral activity of pimecrolimus against dengue virus type 2 infection in vitro and in vivo
Scientific ReportsDengue virus (DENV) infection is a public health concern in several countries and is associated with severe diseases, such as dengue hemorrhagic fever and dengue shock syndrome.
Seong-Ryeol Kim +4 more
doaj +1 more source
2017 HIV Medicine Association of Infectious Diseases Society of America Clinical Practice Guideline for the Management of Chronic Pain in Patients Living With Human Immunodeficiency Virus [PDF]
, 2017 R. Douglas Bruce +9 more
openalex +1 more source
Next‐Generation Bio‐Reducible Lipids Enable Enhanced Vaccine Efficacy in Malaria and Primate Models
Advanced Functional Materials, EarlyView.Structure–activity relationship (SAR) optimization of bio‐reducible ionizable lipids enables the development of highly effective lipid nanoparticle (LNP) mRNA vaccines. Lead LNPs show superior tolerability and antibody responses in rodents and primates, outperforming approved COVID‐19 vaccine lipids.
Ruben De Coen +30 more
wiley +1 more source
Characterization of virus species associated with sweetpotato virus diseases in Burkina Faso. [PDF]
Plant Pathol, 2020 Tibiri EB +7 more
europepmc +1 more source
Anti-foot-and-mouth disease virus effects of Chinese herbal kombucha in vivo [PDF]
, 2015 Naifang Fu +4 more
openalex +1 more source
Implementation of Drug‐Induced Rhabdomyolysis and Acute Kidney Injury in Microphysiological System
Advanced Functional Materials, EarlyView.A modular Muscle–Kidney proximal tubule‐on‐a‐chip integrates 3D skeletal muscle and renal proximal tubule tissues to model drug‐induced rhabdomyolysis and acute kidney injury. The coculture system enables dynamic tissue interaction, functional contraction monitoring, and quantification of nephrotoxicity, revealing drug side effect‐induced metabolic ...
Jaesang Kim +4 more
wiley +1 more source
Neuropathologic Features of Aleutian Disease in Farmed Mink in Ireland and Molecular Characterization of Aleutian Mink Disease Virus Detected in Brain Tissues [PDF]
, 2010 Hanne Jahns +5 more
openalex +1 more source