Results 81 to 90 of about 1,501,773 (255)
Protocol for quantifying miRNA trafficking across the endosomal membrane
FEBS Open Bio, EarlyView.An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh +2 more
wiley +1 more source
Control, elimination, and eradication of river blindness: scenarios, timelines, and ivermectin treatment needs in Africa [PDF]
, 2015 River blindness (onchocerciasis) causes severe itching, skin lesions, and vision impairment including blindness. More than 99% of all current cases are found in sub-Saharan Africa.
Remme, JHF +31 more
core +3 more sources
Bulgarian Journal of Veterinary Medicine, 2021 The paper presents the epizootic and epidemiological situation of rabies in European countries during the last decade. The presented results indicate that the oral immunisation of fox anti-rabies (ORV), used in many European countries, significantly ...
M. Flis
doaj +1 more source
FEBS Open Bio, EarlyView.TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao +10 more
wiley +1 more source
VIRUS ELIMINATION FROM IN VITRO POTATO PLANTS [PDF]
, 2017 The routine and the most effective method of viruses elimination from potato plants is in vitro culture of apical shoots combined with thermo- and/or chemotherapy. At times electrotherapy or cryotherapy is also applied.
Smyda-Dajmund, Paulina
core +4 more sources
Journal of Crop Protection, 2016 Mosaic is presumably the most commonly encountered viral disease in roses. We have developed chemo-thermotherapy for eliminating Arabis mosaic virus (ArMV) and Prunus necrotic ringspot virus (PNRSV) from rose plants.
Amir Modarresi Chahardehi +3 more
doaj
Elimination of mycoplasma contamination of virus stocks
Veterinární Medicína, 2011 We studied the effectivity of a commercial antibiotic kit Mycokill AB for the elimination of mycoplasma contamination in virus strains. The contaminated virus strains were first filtered, treated with Mycokill AB for three hours and repeatedly passaged ...
H. Malenovska, M. Reichelova
doaj +1 more source
Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level
Aging and Cancer, EarlyView.This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley +1 more source
Tomato marchitez virus, a new plant picorna-like virus from tomato related to tomato torrado virus [PDF]
, 2008 A new virus was isolated from a tomato plant from the state of Sinaloa in Mexico. This plant showed symptoms locally known as `marchitez disease¿: severe leaf necrosis, beginning at the base of the leaflets, and necrotic rings on the fruits.
Verbeek, M. +4 more
core +1 more source
Human Vaccines & ImmunotherapeuticsA pivotal study in women aged 16–26 years demonstrated that the nine-valent human papillomavirus (9vHPV) vaccine was efficacious against high-grade cervical dysplasia related to the HPV types covered by the vaccine.
Susanne K. Kjaer +7 more
doaj +1 more source