Results 251 to 260 of about 233,161 (342)

Genetic Encoding of a Trifunctional Photo‐Cross‐Linker with a Cleavable Alkyl Ester Moiety

open access: yesChemBioChem, Volume 27, Issue 3, February 2026.
A novel noncanonical amino acid, DiZAAsu, possessing photo‐cross‐linking, biotinylation, and alkaline‐cleavable functionalities, is genetically encoded by an engineered pyrrolyl‐tRNA synthetase mutant. The alkyl ester moiety expands the design space of cleavable photo‐cross‐linkable amino acids.
Masahiro Takayama   +18 more
wiley   +1 more source

A Masked Intruder: Extranodal Natural Killer/T-Cell Lymphoma Mimicking Preseptal Cellulitis. [PDF]

open access: yesMayo Clin Proc Innov Qual Outcomes
Fuentes SA   +4 more
europepmc   +1 more source

Primary (AL) Amyloidosis Following COVID‐19 Infection: A Case Report

open access: yesClinical Case Reports, Volume 14, Issue 2, February 2026.
ABSTRACT Primary (AL) amyloidosis is a rare systemic disorder caused by extracellular deposition of monoclonal immunoglobulin light chains, resulting in multi‐organ dysfunction. SARS‐CoV‐2 infection may induce persistent inflammatory and immune dysregulation, potentially promoting amyloid formation, although clinical evidence is limited, making the ...
Nasrin Gholami   +4 more
wiley   +1 more source

Adult‐Onset Still's Disease(AOSD) With Features Suggestive of Macrophages Activation Syndrome in Young Female: A Rare Case Report From Nepal

open access: yesClinical Case Reports, Volume 14, Issue 2, February 2026.
ABSTRACT Adult‐onset Still's disease (AOSD) is a rare, multisystem autoinflammatory disorder characterized by a classic triad of fever, evanescent rash, and arthritis with diagnostic challenges. We present a case of a previously healthy 22‐year‐old Nepalese female presented with a 1.5‐month history of progressive bilateral lower limb edema and a 13‐day
Sushil Silwal   +3 more
wiley   +1 more source

T‐cell receptor–like chimeric antigen receptor T cells targeting mesothelin: A first‐in‐human dose‐escalation trial for platinum‐resistant advanced ovarian cancer

open access: yesCancer, Volume 132, Issue 3, 1 February 2026.
Abstract Background Ovarian cancer remains a formidable therapeutic challenge due to late diagnosis, high recurrence rates, and limited treatment options. Mesothelin (MSLN) is highly expressed in ovarian cancer, making it a promising target for immunotherapy.
Yiyang Shan   +7 more
wiley   +1 more source

GPR183‐mediated activation of PI3K is a potential biomarker for immunotherapy in lung cancer

open access: yesClinical and Translational Discovery, Volume 6, Issue 1, February 2026.
Anti‐PD1 treatment and PI3Kγ inhibition had remarkable therapeutic performance on CD4+ Tcm and CD4+ Tn in lung cancer through potential regulation of PI3K pathway with participation of GPR183. Abstract Background As one of commonly used immune checkpoint inhibition therapies, PD1 monoclonal antibodies exhibit a promising cancer immunotherapy approach ...
Ling Ye   +9 more
wiley   +1 more source

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