Results 211 to 220 of about 610,244 (306)

Clinically Relevant Influenza Virus Evolution Reconstituted in a Human Lung Airway-on-a-Chip. [PDF]

Microbiol Spectr, 2021
Si L, Bai H, Oh CY, Jin L, Prantil-Baun R, Ingber DE.   +5 more
europepmc   +1 more source

Expanding Chemical Space of Nucleic Acid Nanoparticles for Tunable Antiviral‐Like Immunomodulatory Responses and Potent Adjuvant Activity

Advanced Functional Materials, EarlyView.
We introduce a nucleic acid nanoparticle (NANP) platform designed to be rrecognized by the human innate immune system in a regulated manner. By changing chemical composition while maintaining constant architectural parameters, we identify key determinants of immunorecognition enabling the rational design of NANPs with tunable immune activation profiles
Martin Panigaj, Hannah S. Newton, Jian Wang, Laxmi Pandey, Yelixza I. Avilla, Phong Nguyen, Morgan Chandler, Justin Halman, Yasmine Radwan, Stephanie Smith, Elijah Edmondson, Simone Difilippantonio, Chelsea Sanders, Bao Tran, Yongmei Zhao, Shaojun Xie, Edward Cedrone, Barry W. Neun, Meni Wanunu, Nikolay V. Dokholyan, Marina A. Dobrovolskaia, Kirill A. Afonin   +21 more
wiley   +1 more source

Tradeoffs between proliferation and transmission in virus evolution- insights from evolutionary and functional analyses of SARS-CoV-2. [PDF]

Virol J
Tai JH, Lee DC, Lin HF, Chao TL, Ruan Y, Cheng YW, Chou YC, Lin YY, Chang SY, Chen PJ, Yeh SH, Wang HY.   +11 more
europepmc   +1 more source

Global dynamics of Porcine Epidemic Diarrhea Virus evolution and transmission

, 2022
Cao Y, Zhang H, Zou C, Peng O, Ashraf U, Xu Q, Gong L, Fan B, Zhang Y, Xu Z, Xue C, Wei X, Zhou Q, Tian X, Shen H, Zhang X, Li B.   +16 more
europepmc   +1 more source

Clinical significance of the binding-activity of polymerized human albumin to the HB virus receptor in relation to evolution of the HBeAg/anti-HBe system in sera from symptom-free carriers and patients

, 1987
Kazuharu Matsuura
openalex   +2 more sources

A Vascular Microphysiological Model of Lung Fibrosis Reveals That Myofibroblasts and IPF Patient‐Derived Fibroblasts Impair Angiogenesis and Vasculogenesis

Advanced Functional Materials, EarlyView.
A microphysiological lung fibrosis model recapitulates myofibroblast–vascular interactions. Induced myofibroblasts and patient‐derived IPF fibroblasts impair angiogenesis and increase vascular permeability via TGF‐β1–driven signaling. Pharmacological interventions with SB 431542 and VEGF supplementation restore vascular morphology and barrier function.
Elena Cambria, Adriana Blazeski, Eunkyung Clare Ko, Tran Thai, Shania Dantes, David A. Barbie, Sarah E. Shelton, Roger D. Kamm   +7 more
wiley   +1 more source

A meta-analysis highlights the idiosyncratic nature of tradeoffs in laboratory models of virus evolution. [PDF]

Virus Evol
Kabengele K, Turner WC, Turner PE, Ogbunugafor CB.   +3 more
europepmc   +1 more source

Immunity, virus evolution, and effectiveness of SARS-CoV-2 vaccines. [PDF]

Braz J Med Biol Res, 2021
Belizário JE.
europepmc   +1 more source

Tailoring the Properties of Functional Materials With N‐Oxides

Advanced Functional Materials, EarlyView.
The properties of materials bearing N‐oxide groups are often dominated by the polar N+─O− bond. It provides hydrophilicity, selective ion‐binding, electric conductivity, or antifouling properties. Many of the underlying mechanisms have only recently been discovered, and the interest in N‐oxide materials is rapidly growing.
Timo Friedrich, Michelle Kobus, Shirin Mesgarha, Erica Moretto, Laurens Grosche, Wolfgang Maison   +5 more
wiley   +1 more source

Identification of novel rodent and shrew orthohepeviruses sheds light on hepatitis E virus evolution. [PDF]

Zool Res
Li FL, Wang B, Han PY, Li B, Si HR, Zhu Y, Yin HM, Zong LD, Tang Y, Shi ZL, Hu B, Yang XL, Zhang YZ.   +12 more
europepmc   +1 more source