Results 151 to 160 of about 635,324 (372)

Distinct genomic integration of MLV and SIV vectors in primate hematopoietic stem and progenitor cells.

PLoS Biology, 2004
Murine leukemia virus (MLV)-derived vectors are widely used for hematopoietic stem cell (HSC) gene transfer, but lentiviral vectors such as the simian immunodeficiency virus (SIV) may allow higher efficiency transfer and better expression. Recent studies
Peiman Hematti, Bum-Kee Hong, Cole Ferguson, Rima Adler, Hideki Hanawa, Stephanie Sellers, Ingeborg E Holt, Craig E Eckfeldt, Yugal Sharma, Manfred Schmidt, Christof von Kalle, Derek A Persons, Eric M Billings, Catherine M Verfaillie, Arthur W Nienhuis, Tyra G Wolfsberg, Cynthia E Dunbar, Boris Calmels   +17 more
doaj   +1 more source

HIV-1 capsid-cyclophilin interactions determine nuclear import pathway, integration targeting and replication efficiency.

PLoS Pathogens, 2011
Lentiviruses such as HIV-1 traverse nuclear pore complexes (NPC) and infect terminally differentiated non-dividing cells, but how they do this is unclear. The cytoplasmic NPC protein Nup358/RanBP2 was identified as an HIV-1 co-factor in previous studies.
Torsten Schaller, Karen E Ocwieja, Jane Rasaiyaah, Amanda J Price, Troy L Brady, Shoshannah L Roth, Stéphane Hué, Adam J Fletcher, KyeongEun Lee, Vineet N KewalRamani, Mahdad Noursadeghi, Richard G Jenner, Leo C James, Frederic D Bushman, Greg J Towers   +14 more
doaj   +1 more source

Integration and Transcription of Virus DNA in Herpes Simplex Virus Transformed Cell Lines

Journal of General Virology, 1980
The physical state of the HSV I DNA present in two biochemically transformed cell lines, a revertant line and a supertransformed cell line, was determined. These cells all contained fragments of the HSV genome and the transformed and supertransformed cell lines expressed virus thymidine kinase.
David T. Kingsbury, Douglas F. Moore
openaire   +3 more sources

The Regulation of Trace Metal Elements in Cancer Ferroptosis

Advanced Biology, EarlyView.
The induction of ferroptosis inhibits tumor growth, enhances anticancer efficacy, and overcomes drug resistance. Recent evidence shows nonferrous metal elements play a role in ferroptosis. This review focuses on how trace metals regulate ferroptosis processes like iron accumulation, lipid peroxidation, and antioxidant defense.
Xiaoyan Wang, Yuanyuan Xue, Lei Chang, Xuena Zhu, Wenjun Liu, Tingbo Liang   +5 more
wiley   +1 more source

Equation-free modeling of evolving diseases: Coarse-grained computations with individual-based models

, 2003
We demonstrate how direct simulation of stochastic, individual-based models can be combined with continuum numerical analysis techniques to study the dynamics of evolving diseases.
Andreasen V., C. William Gear, Earn D., Ioannis G. Kevrekidis, Jaime Cisternas, Simon Levin   +5 more
core   +1 more source

Integration and transcription of mouse mammary tumor virus DNA in rat hepatoma cells. [PDF]

, 1979
G M Ringold, Peter R. Shank, Harold Varmus, J C Ring, Keith R. Yamamoto   +4 more
openalex   +1 more source

POLE3 is a repressor of unintegrated HIV-1 DNA required for efficient virus integration and escape from innate immune sensing. [PDF]

Sci Adv, 2023
Thenin-Houssier S, Machida S, Jahan C, Bonnet-Madin L, Abbou S, Chen HC, Tesfaye R, Cuvier O, Benkirane M.   +8 more
europepmc   +1 more source

Ultra‐Shallow Flat Heat Waves on Low Thermal Conductivity Flexible Polyimide Substrate for Millisecond Thermal Analysis of Materials and Bioelectronic Applications

Advanced Engineering Materials, EarlyView.
An electronic system is presented consisting of a silver thin‐film electrode on a polyimide substrate working both as a heating element and a resistive temperature sensor, generating millisecond heat pulses with very fast heating and cooling rates and a flat peak temperature with a tunable duration.
Bahman K. Boroujeni, Jan Frede, Simon T. Herrmann, Natalie Heinen, Hans Kleemann, Stephanie Pfaender   +5 more
wiley   +1 more source

Interaction of HIV-1 integrase with polypyrimidine tract binding protein and associated splicing factor (PSF) and its impact on HIV-1 replication

Retrovirology, 2019
Background The different interactions between viral proteins and cellular host proteins are required for efficient replication of HIV-1. Various reports implicated host cellular proteins as a key factor that either interact directly with HIV-1 integrase (
Pooja Yadav, Souvik Sur, Dipen Desai, Smita Kulkarni, Vartika Sharma, Vibha Tandon   +5 more
doaj   +1 more source

Analysis of cellular integration sites in avian sarcoma virus infected duck embryo cells [PDF]

, 1979
Tona M. Gilmer, J. Thomas Parsons
openalex   +1 more source