Results 201 to 210 of about 194,914 (262)

Serotonergic System‐Targeted Nucleic Acid Hydrogel Coordinates Excitability Restoration and Circuit Reconstruction for Spinal Cord Injury Therapy

Advanced Materials, EarlyView.
The study reports a DNA/RNA heteroduplex hydrogel (SeroPTEN‐CG) that undergoes DNase‐mediated hydrogel‐to‐nanogel transition for spinal cord injury therapy by targeting the serotonergic system, combining 5‐hydroxytryptamine (5‐HT)‐mediated excitability restoration to reactivate dormant interneurons with phosphatase and tensin homolog (PTEN)‐targeted ...
Chunlin Li, Xiaoqing Zhao, Kai Jiang, Haixia Kang, Shuo Liu, Linlin Jiang, Baoshuai Bai, Haonan Cui, Ziyang Zhang, Menglei Dong, Ruizhi Zhang, Chenbo Zou, Shenghui Shang, Chi Zhang, Xiangchuang Fan, Lijuan Zhu, Huiquan Duan, Chuan Zhang, Shiqing Feng, Hengxing Zhou   +19 more
wiley   +1 more source

Selection for avian leukosis virus integration sites determines the clonal progression of B-cell lymphomas. [PDF]

PLoS Pathog, 2017
Malhotra S, Winans S, Lam G, Justice J, Morgan R, Beemon K.   +5 more
europepmc   +1 more source

Implantable Microarray Patch: Engineering at the Nano and Macro Scale for Sustained Therapeutic Release via Synthetic Biodegradable Polymers

Advanced Materials Technologies, Volume 10, Issue 6, March 18, 2025.
This review focuses on the application of synthetic biodegradable microarray patches (MAPs) in sustained drug delivery. Compared to conventional MAPs which release drugs into the skin in an immediate manner, these implantable MAPs release drugs into skin microcirculation gradually as the biodegradable polymers degrade, thus offering sustained release ...
Li Zhao, Akmal Hidayat Bin Sabri, Mary B. McGuckin, Linlin Li, Zihao Wang, Eneko Larrañeta, Ryan F. Donnelly   +6 more
wiley   +1 more source

Photonic Crystal Enhanced Microscopy on a 2D Photonic Crystal Surface

Advanced Materials Technologies, Volume 10, Issue 6, March 18, 2025.
This work demonstrates the design, fabrication, and the first‐time test of a 2D photonic crystal surface for photonic resonator absorption microscopy. The designed surface uniformly enhances electromagnetic near fields, achieving > 100% improved detecting uniformity for surface‐captured AuNPs from a blocking biosensor assay aimed for detecting SARS‐CoV‐
Weinan Liu, Siyan Li, Edmond Chow, Seemesh Bhaskar, Ying Fang, Brian T. Cunningham   +5 more
wiley   +1 more source

Spider Silk–Integrated Biomimetic Micropillars With Dual Adhesion for Improved Wound Hemostasis and Healing

Advanced Materials Technologies, EarlyView.
The patch mimics the dual physicochemical adhesion mechanisms of gecko toe micropillars and spider silk proteins, enabling strong interfacial bonding via partially cured micropillars. Its facile fabrication allows customization for precision medicine, while its motion responsiveness offers potential for real‐time wound monitoring.
Chengxin Luan, Meng Wei, Xinran Chen, Ni Gan, Bingbing Gao   +4 more
wiley   +1 more source

Femtosecond‐Laser‐Fabricated 3D CYTOP Microfluidic Chips Enabling Super‐Resolution Live Imaging of Cell Behavior in Confined Microspaces

Advanced Materials Technologies, EarlyView.
Using two‐photon polymerization of SU‐8 together with mold processing allowed the creation of defect‐free, flexible 3D microfluidic structures with sub‐micrometer precision in CYTOP. The fabricated CYTOP microfluidic chips enabled super‐resolution imaging of cancer cells in the microchannels, clearly visualizing previously undetectable fine structural ...
Koji Sugioka, Mirai Hanzawa, Kotaro Obata, Sota Matsumoto, Masatoshi Takagi, Asako Sakaue‐Sawano, Asako Tosaki, Satoshi Shimozono, Felix Sima, Hiroyuki Kawano, Takuro Tojima, Daisuke Miyashiro, Kazunari Ozasa, Yasutaka Hanada, Godai Miyaji, Akihiko Nakano, Atsushi Miyawaki   +16 more
wiley   +1 more source

Flux Analysis of the Supercapacitor Performance at Component Level

Advanced Materials Technologies, EarlyView.
The central objective of this study is to introduce new approach and metrics for analyzing the supercapacitor performance at the component level. The lack of standardized evaluation methodologies for analyzing the nonlinear behavior of real system is critical and hinders progress of supercapacitor.
Hyacinthe Randriamahazaka, Van Bui‐Thi‐Tuyet, Christine Ranjan   +2 more
wiley   +1 more source

Exploring the molecular and biological mechanisms of host response in chickens infected with highly pathogenic avian influenza virus (H5N1): An integrative transcriptomic analysis

Sare Golpasand, Shahrokh Ghovvati, Zahra Pezeshkian   +2 more
openalex   +1 more source

Quasi‐Bound States in the Continuum on the Bloch‐Surface‐Wave Platform for Sensing With Simultaneous High Q‐Factor and High Sensitivity

Advanced Optical Materials, EarlyView.
Quasi‐bound states in the continuum on the Bloch surface wave platform are demonstrated, exhibiting high Q‐factors due to strongly suppressed radiative losses and high sensitivity arising from the large evanescent field inherent to the surface wave. The resonance shows clear shifts after each surface molecular functionalization step, highlighting its ...
Bo‐Wei Lin, Mu‐Hsin Chen, Yang‐Chun Lee, Tang Dang, Di Xing, Hiroaki Matsui, Jean‐Jacques Delaunay   +6 more
wiley   +1 more source

A Graph Based Framework to Model Virus Integration Sites. [PDF]

Comput Struct Biotechnol J, 2016
Fronza R, Vasciaveo A, Benso A, Schmidt M.   +3 more
europepmc   +1 more source