Integrated reproductive health: the Zika virus [PDF]
In February 2016, the World Health Organisation (WHO) announced a Public Health Emergency of International Concern following the identification of a cluster of cases of microcephaly reported in Bra...
Fiona Alderdice+1 more
openaire +2 more sources
Improving the identification of antigenic sites in the H1N1 Influenza virus through accounting for the experimental structure in a sparse hierarchical Bayesian model [PDF]
Understanding how genetic changes allow emerging virus strains to escape the protection afforded by vaccination is vital for the maintenance of effective vaccines. In the current work, we use structural and phylogenetic differences between pairs of virus strains to identify important antigenic sites on the surface of the influenza A(H1N1) virus through
arxiv +1 more source
The HETDEX Instrumentation: Hobby-Eberly Telescope Wide Field Upgrade and VIRUS [PDF]
The Hobby-Eberly Telescope (HET) Dark Energy Experiment (HETDEX) is undertaking a blind wide-field low-resolution spectroscopic survey of 540 square degrees of sky to identify and derive redshifts for a million Lyman-alpha emitting galaxies (LAEs) in the redshift range 1.9 < z < 3.5. The ultimate goal is to measure the expansion rate of the Universe at
arxiv +1 more source
VirusDIP: Virus Data Integration Platform [PDF]
AbstractMotivationThe Coronavirus Disease 2019 (COVID-19) pandemic poses a huge threat to human public health. Viral sequence data plays an important role in the scientific prevention and control of epidemics. A comprehensive virus database will be vital useful for virus data retrieval and deep analysis.
Xueqin Guo+25 more
openaire +2 more sources
Cytolytic T lymphocyte recognition of the murine cytomegalovirus nonstructural immediate-early protein pp89 expressed by recombinant vaccinia virus [PDF]
The murine immediate-early (IE) protein pp89 is a nonstructural virus- encoded phosphoprotein residing in the nucleus of infected cells, where it acts as transcriptional activator.
Bertholet, Christine+4 more
core +4 more sources
Synthesis and Integration of Avian Sarcoma Virus DNA [PDF]
In this paper, we have presented data regarding the integration of viral DNA and the persistence of unintegrated viral DNA. We know that integration occurs with specificity with respect to the viral genome, and yet it remains to be established which, if any, of the unintegrated DS DNA species-either the linear or the covalently closed circular forms-is
C. Yeater+3 more
openaire +2 more sources
Exploring the SARS-CoV-2 virus-host-drug interactome for drug repurposing [PDF]
Coronavirus Disease-2019 (COVID-19) is an infectious disease caused by the SARS-CoV-2 virus. It was first identified in Wuhan, China, and has since spread causing a global pandemic. Various studies have been performed to understand the molecular mechanisms of viral infection for predicting drug repurposing candidates.
arxiv +1 more source
Distribution and conservation of Banana Streak Virus (BSV) within banana Musa balbisiana genome: what impact on host and virus evolution ? [PDF]
The nuclear genome of several plants isinvaded by numerous viral sequences. These integrations correspond to accidental events mainly resulting from illegitimate recombination of DNA viruses belonging to the family Caulimoviridae with plant DNA whereas ...
Chabannes, Matthieu+4 more
core +2 more sources
Integration and Lysogeny by an Enveloped Mycoplasma Virus
The 11.8 kilobase pair (7.8 X 10(6) mol. wt.) genome of mycoplasma virus L2 in lysogenic Acholeplasma laidlawii cells was examined. For this study, DNAs were analysed by agarose gel electrophoresis and viral DNA sequences identified by DNA-DNA hybridization.
Jack Maniloff, Kevin Dybvig
openaire +3 more sources
HBV DNA Integration: Molecular Mechanisms and Clinical Implications
Chronic infection with the Hepatitis B Virus (HBV) is a major cause of liver-related morbidity and mortality. One peculiar observation in cells infected with HBV (or with closely‑related animal hepadnaviruses) is the presence of viral DNA integration in ...
Thomas Tu+3 more
doaj +1 more source