Results 71 to 80 of about 635,324 (372)
Site-specific integration by adeno-associated virus. [PDF]
Proceedings of the National Academy of Sciences, 1990 Cellular sequences flanking integrated copies of the adeno-associated virus (AAV) genome were isolated from a latently infected clonal human cell line and used to probe genomic blots derived from an additional 21 independently derived clones of human cells latently infected with AAV.
Kotin RM +9 more
openaire +2 more sources
Methods for evaluating the performance of volume phase holographic gratings for the VIRUS spectrograph array [PDF]
, 2012 The Visible Integral Field Replicable Unit Spectrograph (VIRUS) is an array of at least 150 copies of a simple, fiber-fed integral field spectrograph that will be deployed on the Hobby-Eberly Telescope (HET) to carry out the HET Dark Energy Experiment (HETDEX). Each spectrograph contains a volume phase holographic grating as its dispersing element that
arxiv +1 more source
The power of microRNA regulation—insights into immunity and metabolism
FEBS Letters, EarlyView.MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto +2 more
wiley +1 more source
Integrated dataset for air travel and reported Zika virus cases in Colombia (Data and Resources Paper) [PDF]
arXiv, 2023 This open-access dataset provides consistent records of air travel volumes between 205 airport catchments in Colombia and the associated number of reported human cases of Zika virus within these catchments during the arbovirus outbreak between October 2015 and September 2016.
arxiv
Impact of LEDGIN treatment during virus production on residual HIV-1 transcription
Retrovirology, 2019 Background Persistence of latent, replication-competent provirus is the main impediment towards the cure of HIV infection. One of the critical questions concerning HIV latency is the role of integration site selection in HIV expression. Inhibition of the
Gerlinde Vansant +8 more
doaj +1 more source
Intramolecular integration within Moloney murine leukemia virus DNA [PDF]
, 1981 By screening a library of unintegrated, circular Moloney murine leukemia virus (M-MuLV) DNA cloned in lambda phage, we found that approximately 20% of the M-MuLV DNA inserts contained internal sequence deletions or inversions.
Baltimore, David +3 more
core
LDLR-Gene therapy for familial hypercholesterolaemia: Problems, progress, and perspectives [PDF]
, 2010 Coronary artery diseases (CAD) inflict a heavy economical and social burden on most populations and contribute significantly to their morbidity and mortality rates.
Al-Allaf, FA +5 more
core +3 more sources
BATVI: Fast, sensitive and accurate detection of virus integrations [PDF]
BMC Bioinformatics, 2017 The study of virus integrations in human genome is important since virus integrations were shown to be associated with diseases. In the literature, few methods have been proposed that predict virus integrations using next generation sequencing datasets.
Chandana Tennakoon +3 more
openaire +3 more sources
FEBS Letters, EarlyView.In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley +1 more source
Towards a Functional Cure of HIV-1: Insight Into the Chromatin Landscape of the Provirus
Frontiers in Microbiology, 2021 Despite potent combination antiretroviral therapy, HIV-1 infection persists due to irreversible integration of the virus in long-living cells of the immune system.
Julie Janssens +3 more
doaj +1 more source