Results 61 to 70 of about 1,696,709 (253)

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

Akabane virus isolated from biting midges and its infection in local domestic animal, Yunnan, China: a field and laboratory investigation

Frontiers in Cellular and Infection Microbiology
IntroductionWe verified that Akabane virus (AKAV) is transmitted through biting midges and infects local domestic animals.MethodsIn 2013, viruses were isolate from biting midges in Yunnan, China, using BHK-21 and C6/36 cells. Two AKAV strains (No. 52 and
Jinxin Meng, Yuwen He, Nan Li, Zhenxing Yang, Si Fu, Dongmei Wang, Aiguo Xin, Jinglin Wang, Guodong Liang   +8 more
doaj   +1 more source

The machine learning model based on trajectory analysis of ribonucleic acid test results predicts the necessity of quarantine in recurrently positive patients with SARS-CoV-2 infection

Frontiers in Public Health, 2022
BackgroundSARS-CoV-2 patients re-experiencing positive nucleic acid test results after recovery is a concerning phenomenon. Current pandemic prevention strategy demands the quarantine of all recurrently positive patients.
Qi-Xiang Song, Zhichao Jin, Weilin Fang, Chenxu Zhang, Chi Peng, Min Chen, Xu Zhuang, Wei Zhai, Jun Wang, Min Cao, Shun Wei, Xia Cai, Lei Pan, Qingrong Xu, Junhua Zheng   +14 more
doaj   +1 more source

Yellow fever outbreak, Imatong, southern Sudan. [PDF]

, 2004
In May 2003, the World Health Organization received reports about a possible outbreak of a hemorrhagic disease of unknown cause in the Imatong Mountains of southern Sudan.
Sang, Rosemary C, Victor O. Ofula, Onyango, Clayton O, Ofula, Victor O, Rodney L. Coldren, Robert Swanepoel, Coldren, Rodney L, Burt, Felicity J, Kevin M. De Cock, Rosemary C. Sang, Okoth, Fredrick A, Tukei, Peter M, Samson L. Konongoi, Abdourahmane Sow, Peter M. Tukei, De Cock, Kenin M, Waters, Norman C, Felicity J. Burt, Sow, Abourahmane, Norman C. Waters, Clayton O. Onyango, Fredrick A. Okoth, Konongoi, Sanson L, Clayton O. Onyango, Swanepoel, Robert   +24 more
core   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Isolation and Properties of the Replicase of Encephalomyocarditis Virus [PDF]

Journal of Virology, 1976
The RNA-dependent RNA polymerase (replicase) of encephalomyocarditis (EMC) virus was found to be closely associated with the smooth membranes of infected BHK-21 cells. An RNA-dependent EMC replicase was extracted from the membranes with 0.15% sodium dodecyl sulfate (SDS) and 1,1,2-trichlorotri-fluoroethane (Genetron 113) and further purified by high ...
A, Traub, B, Duskin, H, Rosenberg, E, Kalmar   +3 more
openaire   +2 more sources

Prospecting the protein design landscape

FEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona, Katharina T. Stonig, Jens Meiler, Clara T. Schoeder, Monica L. Fernández‐Quintero   +4 more
wiley   +1 more source

The ubiquitin system in normal and infected germinal center B cells

FEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis, Lesly Mejia, Emily K Moser   +2 more
wiley   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Isolation and Characterization of Contemporary Bovine Coronavirus Strains

Viruses
Bovine coronavirus (BCoV) poses a threat to cattle health worldwide, contributing to both respiratory and enteric diseases. However, few contemporary strains have been isolated.
Yu Li, Roberto A. Palomares, Mingde Liu, Jiayu Xu, Chohee Koo, Francesca Granberry, Samantha R. Locke, Greg Habing, Linda J. Saif, Leyi Wang, Qiuhong Wang   +10 more
doaj   +1 more source