Nanoreactors: Strategies to encapsulate enzyme biocatalysts in virus-like particles.
New Biotechnology, 2018 Enzyme-mediated biocatalysis is generally more selective and environmentally friendly and requires less energy than chemocatalysis. However, factors such as temperature, acidity and the presence of proteases can negate enzyme activity.
Joshua W Wilkerson +4 more
semanticscholar +1 more source
Dengue virus-like particles mimic the antigenic properties of the infectious dengue virus envelope
Virology Journal, 2018 BackgroundThe 4 dengue serotypes (DENV) are mosquito-borne pathogens that are associated with severe hemorrhagic disease. DENV particles have a lipid bilayer envelope that anchors two membrane glycoproteins prM and E.
Stefan W. Metz +6 more
semanticscholar +1 more source
Exploiting virus-like particles as innovative vaccines against emerging viral infections
Journal of Microbiology, 2017 Emerging viruses pose a major threat to humans and livestock with global public health and economic burdens. Vaccination remains an effective tool to reduce this threat, and yet, the conventional cell culture often fails to produce sufficient vaccine ...
Hotcherl Jeong, B. Seong
semanticscholar +1 more source
Use of recombinant virus replicon particles for vaccination against Mycobacterium ulcerans disease [PDF]
, 2015 Buruli ulcer, caused by infection with Mycobacterium ulcerans, is a necrotizing disease of the skin and subcutaneous tissue, which is most prevalent in rural regions of West African countries.
Bolz, Miriam +3 more
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Antiviral Research, 2016 Middle East respiratory syndrome coronavirus (MERS‐CoV) has continued spreading since its emergence in 2012 with a mortality rate of 35.6%, and is a potential pandemic threat.
Chong Wang +16 more
semanticscholar +1 more source
Virus-like particle-based vaccines targeting the Anopheles mosquito salivary protein TRIO
mSphereMalaria is a highly lethal infectious disease caused by Plasmodium parasites. These parasites are transmitted to vertebrate hosts when mosquitoes of the Anopheles genus probe for a blood meal.
Alexandra Francian +5 more
doaj +1 more source
Virus-like particles: innate immune stimulators
Expert Review of Vaccines, 2011 Sub-virion particles, now known as virus-like particles (VLPs), were first purified from plasma samples of hepatitis B virus-infected patients in 1968 [1].
openaire +2 more sources
Purification of HIV-1 gag virus-like particles and separation of other extracellular particles.
Journal of Chromatography A, 2016 Enveloped virus-like particles (VLPs) are increasingly used as vaccines and immunotherapeutics. Frequently, very time consuming density gradient centrifugation techniques are used for purification of VLPs.
Petra Steppert +10 more
semanticscholar +1 more source
The 5th virus-like particle and nano-particle vaccines (VLPNPV) conference
Expert Review of Vaccines, 2019 Virus-like particles (VLPs) and nano-particles (NPs) are promising vaccine platforms that have led to the successful development of commercially available vaccines.
Paul Engeroff, Martin F. Bachmann
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Modular Virus-Like Particles: Building Nanoscale Platforms for Multiple Applications
Postępy MikrobiologiiVirus-like particles (VLPs) are multiprotein structures that mimic the conformation of infectious virus particles and are therefore potent inducers of immune responses in mammals.
Naskalska Antonina
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