Results 21 to 30 of about 1,034,821 (62)

Influenza virus activation of the interferon system [PDF]

open access: yes, 2015
This study was supported by the Wellcome Trust (grant number 087751/A/08/Z) and the Medical Research Council (grant number G0700848).The host interferon (IFN) response represents one of the first barriers that influenza viruses must surmount in order to ...
Fodor, Ervin   +8 more
core   +1 more source

Arming vaccinia virus for pancreatic cancer oncolytic virotherapy [PDF]

open access: yes, 2011
PhDVaccinia virus is a 250-300nm enveloped DNA virus from the poxvirus family and is used as a vector for oncolytic viral gene therapy. No unique cell surface receptor has been identified for Vaccinia virus and the reasons for its tropism for cancer ...
Hiley, Crispin
core   +4 more sources

Cellular phosphoinositides and the maturation of bluetongue virus, a non-enveloped capsid virus. [PDF]

open access: yes, 2013
BACKGROUND: Bluetongue virus (BTV), a member of Orbivirus genus in the Reoviridae family is a double capsid virus enclosing a genome of 10 double-stranded RNA segments. A non-structural protein of BTV, NS3, which is associated with cellular membranes and
Roy, Polly   +3 more
core   +1 more source

Global patterns in monthly activity of influenza virus, respiratory syncytial virus, parainfluenza virus, and metapneumovirus: a systematic analysis

open access: yes, 2019
Background: Influenza virus (IFV), respiratory syncytial virus (RSV), parainfluenza virus (PIV), and metapneumovirus (MPV) are the most common viruses associated with acute lower respiratory infections in young children and the elderly.
Nair, Harish, Li, You
core   +1 more source

Cloned defective interfering influenza virus protects ferrets from pandemic 2009 influenza A virus and allows protective immunity to be established [PDF]

open access: yes, 2012
Influenza A viruses are a major cause of morbidity and mortality in the human population, causing epidemics in the winter, and occasional worldwide pandemics.
Cheung, Linda   +39 more
core   +2 more sources

Low dose influenza virus challenge in the ferret leads to increased virus shedding and greater sensitivity to oseltamivir [PDF]

open access: yes, 2014
Ferrets are widely used to study human influenza virus infection. Their airway physiology and cell receptor distribution makes them ideal for the analysis of pathogenesis and virus transmission, and for testing the efficacy of anti-influenza ...
Dove, Brian K.   +35 more
core   +1 more source

Tomato chocolàte virus: a new plant virus infecting tomato and a proposed member of the genus Torradovirus [PDF]

open access: yes, 2010
A new virus was isolated from a tomato plant from Guatemala showing necrotic spots on the bases of the leaves and chocolate-brown patches on the fruits.
Verbeek, M.   +11 more
core   +1 more source

Three broad modalities in the natural history of vertically acquired hepatitis C virus infection.

open access: yes, 2005
BACKGROUND: Little is known about the natural history of vertically acquired hepatitis C virus (HCV) infection. METHODS: We performed a large, multicenter, prospective study of children born to HCV-infected women in Europe. Children were considered to
European Paediatric Hepatitis C. Virus Network   +1 more
core   +1 more source

A novel broad-spectrum treatment for respiratory virus infections : influenza-based defective interfering virus provides protection against pneumovirus infection in vivo [PDF]

open access: yes, 2011
Respiratory viruses represent a major clinical burden. Few vaccines and antivirals are available, and the rapid appearance of resistant viruses is a cause for concern.
Edworthy, Nicole Lynn   +11 more
core   +1 more source

Vaccinia virus replication is not affected by APOBEC3 family members [PDF]

open access: yes, 2006
Background: The APOBEC3G protein represents a novel innate defense mechanism against retroviral infection. It facilitates the deamination of the cytosine residues in the single stranded cDNA intermediate during early steps of retroviral infection.
Sutter Gerd   +17 more
core   +1 more source

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