Results 111 to 120 of about 79,932 (217)

Multimodal Chromatography in the Downstream Processing of mAb‐Based Products: Mechanisms, Strategies, and Applications

open access: yesBiotechnology and Bioengineering, Volume 123, Issue 5, Page 1236-1265, May 2026.
ABSTRACT Multimodal chromatography has emerged as a powerful tool for the purification of monoclonal antibodies (mAbs) and their derivatives—including antibody fragments (Fabs), Fc‐fusions, bispecific (BsAb), and antibody–drug conjugates (ADCs)—offering enhanced selectivity through the integration of ionic, hydrophobic, hydrogen‐bonding, and π–π ...
Amin Javidanbardan   +4 more
wiley   +1 more source

Chronic scrotal content pain and viral orchiepididymitis: an overlooked hypothesis linking infection and Wallerian degeneration. [PDF]

open access: yesBasic Clin Androl
Teixeira TA   +6 more
europepmc   +1 more source

Optimizing Pichia Pastoris Cell‐Free Protein Synthesis to Improve Economics

open access: yesBiotechnology and Bioengineering, Volume 123, Issue 6, Page 1708-1720, June 2026.
ABSTRACT Cell‐free protein synthesis (CFPS) is a powerful and versatile platform that supports a wide range of applications, from fundamental studies of the genetic code to scalable and rapid protein production. The recently developed Pichia pastoris CFPS combines advantages of both prokaryotic and eukaryotic systems, including a rapid growth rate ...
Rui Wu   +4 more
wiley   +1 more source

<i>Ex vivo</i> mucosal cultures: an emerging player in vaccine development. [PDF]

open access: yesFront Cell Infect Microbiol
Chilakamarri N, Sallard E, Aydin M.
europepmc   +1 more source

Cold atmospheric plasma‐mediated tumor microenvironment remodeling for cancer treatment

open access: yesBMEMat, EarlyView.
Schematic presentation of CAP‐mediated TME remodeling. This review summarizes recent efforts in cold atmospheric plasma (CAP) application in cancer treatment, highlighting the anticancer potential of CAP, molecular mechanisms, and future perspectives for further improvement and clinical translation.
Israr Khan   +8 more
wiley   +1 more source

Pediatric Autoimmune Sclerosing Cholangitis: Diagnostic and Therapeutic Challenges. [PDF]

open access: yesPediatr Rep
Sucaciu RM   +8 more
europepmc   +1 more source

Transfersomes with core and surface‐loaded NF‐κB p65 siRNA for enhanced transdermal transfection and effective treatment of psoriasis

open access: yesBMEMat, EarlyView.
TCPL, a transfersome with Tween 80 and PEI, enables efficient transdermal siNF‐κB delivery, resolving PEI's toxicity issue. It promotes lysosomal escape and effective transfection, silences NF‐κB, modulates immunity, and inhibits angiogenesis, alleviating psoriasis. With good biocompatibility, TCPL holds strong clinical translation potential. Schematic
Hui Xing   +6 more
wiley   +1 more source

Host, vector, and parasite dynamics: exploring intrinsic and extrinsic factors shaping tick‐borne filarial nematode transmission

open access: yesBiological Reviews, EarlyView.
ABSTRACT Tick‐borne filarial nematodes are a complex and understudied group of parasites that rely on ticks for transmission in vertebrates. This review examines how intrinsic and extrinsic factors may influence the successful transmission of filarial nematodes in tick vectors, drawing insights from extensively studied haematophagous dipteran vector ...
Oluwaseun D. Ajileye   +4 more
wiley   +1 more source

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