Results 161 to 170 of about 952,462 (310)

Detection of enteric viruses in source and treated waters of the city of Hamadan, Iran. [PDF]

PeerJ
Ansari N, Mazaheri Z, Owliaee I, Abbaszadegan M, Alum A, Amini R, Beikpour F, Azizi Jalilian F.   +7 more
europepmc   +1 more source

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan, Yan Jiang, Yuxuan Yong, Tianshuo Zhang, Niannian Zhang, Qianqian Zeng, Xue Gong, Li Meng, Fangfang Bi, Yongmin Liu   +9 more
wiley   +1 more source

Host Species Contribution to the Spatiotemporal Dynamics of the 2024-2025 H5N1 Epidemic in Italy. [PDF]

Influenza Other Respir Viruses
Savegnago E, Cavicchio L, Dianati M, Salomoni A, Zecchin B, Sartori A, Giussani E, Moreno A, Zamperin G, Palumbo E, Schivo A, Salviato A, Ormelli S, Varotto M, Terregino C, Monne I, Fusaro A.   +16 more
europepmc   +1 more source

Influenza Vaccination Responses in Disabled Stroke Patients: A Single‐Center Prospective Observational Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aimed to investigate the immunological response to influenza vaccination, the incidence and severity of influenza infection, and the side effects of the vaccination in patients with ischemic stroke. Methods This prospective observational study was conducted between 2023 and 2024 at Ramathibodi Hospital.
Achiraya Pakngao, Sureerat Suwatcharangoon, Pintip Ngamjanyapron, Kobporn Boonnak, Thanitta Suangtamai, Porpon Rotjanapan   +5 more
wiley   +1 more source

Emerging Oncolytic Viruses: Beyond Adenoviruses and Herpes Simplex Virus. [PDF]

J Cancer
Chokkakula S, Yin C, Yang B, Chong S, Pathakumari B, Zhang YQ, Nirmala PV, Lai KW, Naveen B, Tang Q.   +9 more
europepmc   +1 more source

Movement Disorders in Aicardi–Goutières Syndrome and Response to Immunomodulation

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT This study characterizes movement disorders and treatment responses in seven children with Aicardi–Goutières syndrome (AGS). We retrospectively evaluated motor phenotypes, neuroimaging, and interferon signatures in patients treated with baricitinib or anifrolumab. Spasticity affected all patients, while dystonia was present in 4/7.
Enrique Gonzalez Saez‐Diez, Monica Ferrer Socorro, Kathryn Yang, Nicole Battaglia, Zainab Zaman, Mariko Bennett, Adeline Vanderver, Pui Y. Lee, Lauren A. Henderson, Milena M. Andzelm, Darius Ebrahimi‐Fakhari   +10 more
wiley   +1 more source

Diversity and taxonomy of giant algal viruses: chloroviruses lead the way. [PDF]

J Virol
Rodrigues RAL.
europepmc   +1 more source

Comparative Effectiveness and Safety of Inebilizumab Versus Rituximab in AQP4‐IgG‐Positive NMOSD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rituximab (anti‐CD20, RTX) and inebilizumab (anti‐CD19, INE) represent B‐cell‐depleting therapies used for aquaporin‐4 antibody‐positive (AQP4‐IgG+) neuromyelitis optica spectrum disorder (NMOSD); however, direct comparative evidence remains limited.
Jie Lin, Binbin Xue, Dewei Xie, Jia Li, Juyuan Pan, Lanbing Zhu, Qiaowen Tong, Jing Lin, Ruofan Zhu, Xu Zhang, Junhui Xia, Xiang Li   +11 more
wiley   +1 more source

Assessment of human immunity to A/H3N2 influenza subclade K during 2025 emergence. [PDF]

EBioMedicine
Harvey R, Welsh C, Byrne AM, Greenwood D, Stevenson-Leggett P, Galiano M, Bailey D, Chan YW, Boateng J, Wolmuth-Gordon H, Whitaker H, Brown KE, Jeffery-Smith A, Allen A, Amirthanlingam G, Fossum E, Vikse EL, Rohringer A, Hungnes O, Bragstad K, Swanton C, Williams B, Gandhi S, Gamblin S, Carr EJ, Lewis NS, Wall EC, Wu MY, Crick Serology Pipeline, Legacy Investigators.   +29 more
europepmc   +1 more source

Neurovascular Contacts in the Pathophysiology of Neuralgic Amyotrophy: An Observational Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neuralgic amyotrophy (NA) is a prevalent, monophasic, multifocal immune‐mediated neuropathy. A distinctive characteristic of the disease is the occurrence of nerve or fascicle constrictions and torsions (NA‐associated focal nerve lesions, NAFL). The pathophysiology underlying this phenomenon remains to be fully elucidated.
Johannes Fabian Holle, Andreas Leha, Volker Limmroth, Wolfram Windisch, Maximilian Zimmermann   +4 more
wiley   +1 more source