Next‐Generation Bio‐Reducible Lipids Enable Enhanced Vaccine Efficacy in Malaria and Primate Models
Structure–activity relationship (SAR) optimization of bio‐reducible ionizable lipids enables the development of highly effective lipid nanoparticle (LNP) mRNA vaccines. Lead LNPs show superior tolerability and antibody responses in rodents and primates, outperforming approved COVID‐19 vaccine lipids.
Ruben De Coen +30 more
wiley +1 more source
Viral metagenomic analysis of fecal samples from <i>Bos grunniens</i> on the Qinghai-Tibet Plateau reveals novel picornaviruses and diverse CRESS-DNA viruses. [PDF]
Chen J +8 more
europepmc +1 more source
This study presents the BioCLEAR system, a highly transparent and conductive neural electrode array composed of silver nanowires (AgNWs) and doped PEDOT:PSS, enabling neural recordings with minimal optical artifacts. When integrated with a GRIN lens, this cost‐effective neural implant allows simultaneous electrophysiological recording and GCaMP6‐based ...
Dongjun Han +17 more
wiley +1 more source
Virulence and transmission characteristic of H3N8 avian influenza virus circulating in chickens in China. [PDF]
Mei M, Zhang X, Wu Q, Xu M, Zhao Y.
europepmc +1 more source
Trade-offs between and within scales: environmental persistence and within-host fitness of avian influenza viruses [PDF]
Andreas Handel +3 more
openalex +1 more source
Virioplankton: Viruses in Aquatic Ecosystems
K. Wommack, R. Colwell
semanticscholar +1 more source
A previously unreported coordination motif stabilising single Fe atoms by indigo chelation and pyridyl coordination on Au(111) has been revealed. By using planar tritopic pyridyl linkers (TPyB), extended 2D porous networks of indigo3(TPyB)2Fe6 form. These networks can be crystalline or vitreous and offer an environment where individual coordination ...
Hongxiang Xu +9 more
wiley +1 more source
HA Protein acetylation modulates replication, pathogenicity, and immunogenicity of influenza virus and facilitates live-attenuated vaccine design. [PDF]
Wu M +11 more
europepmc +1 more source
Crystal Structure of Foot-and-Mouth Disease Virus 3C Protease
James R. Birtley +5 more
openalex +1 more source

