Results 281 to 290 of about 3,729,339 (351)

Biologically Active Implants Prevent Mortality in a Mouse Sepsis Model

Advanced Healthcare Materials, EarlyView.
A modular, triple‐action titanium implant is developed to prevent implant‐associated infections by repelling bacteria, killing pathogens, and enhancing tissue integration. Coatings with phage cocktails targeting P. aeruginosa and S. aureus show significant bacterial reduction and improved survival in a mouse sepsis model.
Martin Stark, Fereshteh Bayat, Sara Rahmani, Mathura Thirugnanasampanthar, Taylor Kramer, Elise Schwarz, David Wilson, Jeffrey I. Weitz, Zeinab Hosseinidoust, Tohid F. Didar   +9 more
wiley   +1 more source

Seasonal Influenza Exposure Elicits Functional Antibody and T-cell Responses to A(H5) Influenza Viruses in Humans

Power MA, Rijnink WF, Soochit W, Gommers L, van der Linden A, Chandler F, Volker F, Bestebroer TM, Verstrepen BE, Grifoni A, Tan NH, Bogers S, van Nierop GP, Sette A, Koopmans MP, GeurtsvanKessel CH, Sikkema RS, Richard M, de Vries RD.   +18 more
europepmc   +1 more source

Using homologous network to identify reassortment risk in H5Nx avian influenza viruses. [PDF]

PLoS Comput Biol
Gong R, Feng Z, Zhang Y.
europepmc   +1 more source

An Organ‐on‐Chip Platform for Strain‐Controlled, Tissue‐Specific Compression of Cartilage and Mineralized Osteochondral Interface to Study Mechanical Overloading in Osteoarthritis

Advanced Healthcare Materials, EarlyView.
A mechanically active OsteoChondral Unit (OCU)‐on‐Chip platform mimicking the OCU's functional anatomy and the strain gradient across the osteochondral interface is presented. Upon compartment‐specific hyperphysiological compression, the model replicates mechanisms observed in osteoarthritis (OA) progression, such as calcium crystal accumulation ...
Andrea Mainardi, Anastasiya Börsch, Paola Occhetta, Robert Ivanek, Martin Ehrbar, Lisa Krattiger, Philipp Oertle, Marko Loparic, Ivan Martin, Marco Rasponi, Andrea Barbero   +10 more
wiley   +1 more source

Phylogenetic analysis of H5N1 influenza viruses isolated from dairy cattle in Texas in December 2024. [PDF]

J Virol
Kandel S, Babujee L, Guan L, Dahn R, Pattinson D, Halfmann PJ, Eisfeld AJ, Neumann G, Thompson AC, Alexander Morris ER, Swinford AK, Poulsen K, Dimitrov KM, Kawaoka Y.   +13 more
europepmc   +1 more source

Impact of Nanoparticle Stiffness on Endosomal Escape and Signaling Pathways in Cytosolic Delivery

Advanced Healthcare Materials, EarlyView.
Nanoparticle (NP) stiffness affects cellular uptake, but its impact on intracellular distribution remains unclear. This study synthesizes silica nanocapsules with varying stiffness, inspired by viral mechanisms, and applies assays to measure cellular uptake and escape efficiency.
Yali Zhang, Yue Hui, Zichao Guo, Dawei Liu, Yun Liu, Huajian Gao, Chun‐Xia Zhao   +6 more
wiley   +1 more source

An Update on RNA Virus Discovery: Current Challenges and Future Perspectives. [PDF]

Viruses
Debat H, Bejerman N.
europepmc   +1 more source

Practical Guide to the Design of Granular Hydrogels for Customizing Complex Cellular Microenvironments

Advanced Healthcare Materials, EarlyView.
Granular hydrogels are emerging microporous platforms for cell culture and delivery, showing great potential for replicating the complex, heterogeneous environments found in natural tissues. This review outlines the design principles of granular hydrogels, highlighting critical factors that determine the final physicochemical properties of the entire ...
Shuhan Feng, Kaiyang Chen, Shiqi Wang
wiley   +1 more source

Assessment of Cross-Reactive Neutralizing Antibodies Induction Against H5N1 Clade 2.3.4.4b by Prior Seasonal Influenza Immunization in Retail Workers. [PDF]

Open Forum Infect Dis
Arroyave A, Rabezanahary H, Wantchecon A, Rahajamanana VL, Sahli A, Thériault M, Boudreau D, Gilbert C, Trottier S, Baz M.   +9 more
europepmc   +1 more source