Results 341 to 350 of about 2,061,892 (381)

A positive-sense single-stranded RNA virus acquired a negative-sense open reading frame through recombination. [PDF]

open access: yesPLoS Pathog
Dong X   +15 more
europepmc   +1 more source

Viral‐Mediated Connexin 26 Expression Combined with Dexamethasone Rescues Hearing in a Conditional Gjb2 Null Mice Model

open access: yesAdvanced Science, EarlyView.
AAV2.7m8 serotype combined with the gfaABC1D promoter targets infection of supporting cells (SCs). AAV2.7m8‐gfaABC1D‐Gjb2 administration to mice results in excessive immune responses. The combination of AAV2.7m8‐gfaABC1D‐Gjb2 with dexamethasone (DEX) shows a synergistic effect and enhances the gene therapy effect in a conditional Cx26 null mice model ...
Xiaohui Wang   +8 more
wiley   +1 more source

Activation of Glutamatergic Neurons in the Supramammillary Nucleus Promotes the Recovery of Consciousness under Sevoflurane Anesthesia

open access: yesAdvanced Science, EarlyView.
Selective lesioning of SuM glutamatergic neurons promoted the induction of and delayed emergence from sevoflurane anesthesia and increased sevoflurane sensitivity. Optogenetic stimulation of SuM glutamatergic neurons or the SuM‐MS projection promoted behavioral arousal and cortical activation under steady‐state sevoflurane anesthesia and reduced the ...
Jiayan Li   +8 more
wiley   +1 more source

Viral infections and immune modulation in bladder cancer: implications for immunotherapy. [PDF]

open access: yesExplor Target Antitumor Ther
Pascoal LB   +8 more
europepmc   +1 more source

Influenza A(H1N1)pdm09 Virus with Reduced Susceptibility to Baloxavir, Japan, 2024. [PDF]

open access: yesEmerg Infect Dis
Takashita E   +17 more
europepmc   +1 more source

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