Results 81 to 90 of about 1,054,067 (301)

Evaluation of different genomic regions of rotavirus B and rotavirus C for development of real-time RT‒PCR assays

Virology Journal
Background The causative agents of diarrhea, rotavirus B (RVB) and rotavirus C (RVC) are common in adults and patients of all age groups, respectively.
Madhuri S. Joshi, Manohar S. Shinde, Mallika Lavania   +2 more
doaj   +1 more source

Prospecting the protein design landscape

FEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona, Katharina T. Stonig, Jens Meiler, Clara T. Schoeder, Monica L. Fernández‐Quintero   +4 more
wiley   +1 more source

Microbiome composition modulates the lethal outcome of Drosophila A virus infection

Cellular and Molecular Life Sciences
Host-associated microbiomes can strongly influence viral infection outcomes, yet how minor variations in commensal bacterial composition modulate viral pathogenesis remain poorly understood.
Rubén­ González, Mauro Castelló-Sanjuán, Ottavia Romoli, Hervé Blanc, Hiroko Kobayashi, Jared Nigg, Maria-Carla Saleh   +6 more
doaj   +1 more source

Emergence of a novel reassortant highly pathogenic avian influenza clade 2.3.4.4b A(H5N2) Virus, 2024

Emerging Microbes and Infections
Reassortant highly pathogenic avian influenza A(H5N2) clade 2.3.4.4.b viruses were detected from ducks and environmental samples in Egypt, June 2024. Genomic and phylogenetic analyses revealed a novel genotype produced by the reassortment of an A(H5N1 ...
Rabeh El-Shesheny, Mokhtar Gomaa, Mohamed El Sayes, Mina Nabil Kamel, Ahmed El Taweel, Omnia Kutkat, Mohamed GabAllah, Amany Elkhrsawy, Hager Emam, Yassmin Moatasim, Ahmed Kandeil, Pamela P. McKenzie, Richard J. Webby, Mohamed Ahmed Ali, Ghazi Kayali   +14 more
doaj   +1 more source

The ubiquitin system in normal and infected germinal center B cells

FEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis, Lesly Mejia, Emily K Moser   +2 more
wiley   +1 more source

Complete genome sequencing and comparative phylogenomics of nine African Swine Fever Virus (ASFV) isolates of the virulent East African p72 genotype IX without viral sequence enrichment [PDF]

African swine fever virus (ASFV) is endemic to African wild pigs (Phacochoerus and Potamochoerus), in which viral infection is asymptomatic, and Ornithodoros soft ticks. However, ASFV causes a lethal disease in Eurasian domestic pigs (Sus scrofa).
Machuka, Eunice M., Cynthia Kavulani Onzere, Chris Upton, Onzere, Cynthia Kavulani, Bishop, Richard P., Richard P. Bishop, Upton, Chris, Edwina Bochere, Domelevo Entfellner, Jean-Baka, Okoth, Edward Abworo, Höper, Dirk, Emma Peter Njau, Bochere, Edwina, Jean-Baka Domelevo Entfellner, Samuel O. Oyola, Oyola, Samuel O., Sonal P. Henson, Edward Abworo Okoth, Dirk Höper, Eunice M. Machuka, Henson, Sonal P., Njau, Emma Peter   +21 more
core   +1 more source

Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis

FEBS Letters, EarlyView.
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng, Shen‐Shin Chang, Feng‐Wei Chen, Ying‐Chieh Su, Thanh Phuong Nguyen, Yu‐Wei Hsiao, Jhih‐Ying Chi, Hsin‐Yin Liang, Ju‐Ming Wang   +8 more
wiley   +1 more source

Viruses, Viruses, Viruses [PDF]

, 2004
They're in the news every day-flu, HIV, SARS, bioweapons. And many of the discoveries of molecular biology were made with viruses.
Baltimore, David
core  

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

FEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

The Abundance and Behavior of Viruses in Ancient Seawater and Modern Iron-rich Environments [PDF]

, 2011
The proclivity of silica for ferric hydroxide sorption sites allows for an Archean iron cycle involving iron-silica co-precipitation and deposition of banded iron formations (BIF).
Liu, Hanna Ken-Yuin
core   +1 more source