Results 21 to 30 of about 147,286 (225)

Visceral leishmaniasis complicated by hemophagocytic lymphohistiocytosis: A case report from a nonendemic area

Clinical Case Reports, 2023
Key Clinical Message Visceral leishmaniasis and hemophagocytic lymphohistiocytosis share many features in common and may coincide in the same patient. Timely diagnosis and management of visceral leishmaniasis could save patients from unnecessary toxic ...
Anwar I. Joudeh, Hussein A. Elsiddig Awadelkarim, Mohammadshah Isam Gul, Mahmoud Salm Elayana, Dina Sameh Soliman, Aliaa Amer, Musaed Alsamawi   +6 more
doaj   +1 more source

Synthesis, Antiparasitic Activity, and ADME Profile of Morpholinephenylbenzamides: A Pharmacological Study Against Chagas Disease and Visceral Leishmaniasis [PDF]

ChemMedChem
Hit‐to‐lead optimization of morpholinephenylbenzamides reveals key structure–activity relationships against Trypanosoma cruzi and Leishmania infantum. Potency, selectivity, and ADME properties are differentially improved across the series, identifying compounds 20, 24, and 16 as complementary templates for the future design of dual antiparasitic leads.
Farago D, de Melo Resende D, de Moura Lodi Cruz M, Sousa R, Chelucci R, Michelan‐Duarte S, da Silva Mendonça de Melo F, da Silva Oliveira D, Macruz P, dos Santos Carvalho A, Pilau E, Bastos I, Andricopulo A, Ferreira L, Murta S, de Oliveira Rezende Júnior C.   +15 more
europepmc   +2 more sources

Efficacy and Safety of Paromomycin for Visceral Leishmaniasis: A Systematic Review

Journal of Tropical Medicine, 2021
Visceral leishmaniasis, also known as kala-azar is one of the most commonly neglected tropical diseases affecting a large number of rural and resource-limited people in South Asia, Africa, and South America.
Pashupati Pokharel, Rakesh Ghimire, Pratik Lamichhane   +2 more
doaj   +1 more source

Immunobiology of visceral leishmaniasis [PDF]

Frontiers in Immunology, 2012
Visceral leishmaniasis (VL), commonly known as kala-azar, is caused by Leishmania donovani and Leishmania infantum (Leishmania chagasi in the Americas). These Leishmania species infect macrophages throughout the viscera, and parasites are typically found in the spleen, liver, and bone marrow.
Kumar, Rajiv, Nylén, Susanne
openaire   +3 more sources

Insights from mathematical modelling and quantitative analysis on the proposed WHO 2030 targets for visceral leishmaniasis on the Indian subcontinent [version 1; peer review: 2 approved]

Gates Open Research, 2019
Visceral leishmaniasis (VL) is a neglected tropical disease (NTD) caused by Leishmania protozoa that are transmitted by female sand flies. On the Indian subcontinent (ISC), VL is targeted by the World Health Organization (WHO) for elimination as a public
NTD Modelling Consortium Visceral Leishmaniasis Group
doaj   +1 more source

Diagnosis of visceral leishmaniasis [PDF]

Transactions of the Royal Society of Tropical Medicine and Hygiene, 2011
Leishmaniasis is a vector-borne disease with up to 350 million people at risk of infection worldwide. Among its different clinical manifestations, visceral is the most severe form. Since clinical features of visceral leishmaniasis (VL) mimic several other common diseases, accurate diagnosis is crucial as the treatment is associated with significant ...
Pankaj, Srivastava, Anand, Dayama, Sanjana, Mehrotra, Shyam, Sundar   +3 more
openaire   +2 more sources

Sodium Stibogluconate (SSG) & Paromomycin Combination Compared to SSG for Visceral Leishmaniasis in East Africa: A Randomised Controlled Trial [PDF]

, 2012
Alternative treatments for visceral leishmaniasis (VL) are required in East Africa.
Makonnen, Eyasu, Khalil Eltahir, Eltahir Khalil (156978), Musa, Ahmed, Ahmed El-Hassan (157032), Abuzaid Abdalla Abuzaid (157013), Kesusu, Josephine, Yifru Sisay, Mbui Jane, Sisay Yifru, Hailu, Workagegnehu, Raymond Omollo, Serah Ndegwa, Juma Rashid (156998), Fadlalla, Ahmed, Geoffrey Mutuma (157058), Weldegebreal Teklu, Teklu Weldegebreal, Zewdu Hurissa, Rhoda Owiti, Marius Mueller (157039), Brima Musa, Raymond Omollo (156992), Tafes Hailemariam, Kesusu Josephine, Teklu Weldegebreal (101974), Mengistu, Getahun, Ahmed El-Hassan, Hailemariam Tafes, Osama Ahmed (157018), Tafes, Hailemariam, Ahmed Musa (156973), Brima Musa (157009), Geoffrey Mucee, Kimutai, Robert, Sagaki Patrick, Joseph Olobo (156982), El-Hassan Ahmed, Olobo Joseph, Omollo Raymond, George Kirigi (157066), Robert Kimutai (157106), Lodenyo Hudson, Hailemariam Tafes (157080), Simon Njoroge, Mutuma Geoffrey, Ndegwa, Serah, Workagegnehu Hailu, Edwards, Tansy, Balasegaram Manica, Tansy Edwards (122527), Eltahir Khalil, Juma Rashid, Olobo, Joseph, Hudson Lodenyo, Apadet Lilian, Sagaki, Patrick, Njoroge, Simon, Robert Kimutai, Sisay Yifru (157068), George Kirigi, Njoroge Simon, Getahun Mengistu (157072), Hailu Asrat, Hudson Lodenyo (157062), Hurissa Zewdu, Ellis Sally, Mueller Marius, Abuzaid, Abuzaid Abdalla, Mutea Dedan, Mucee, Geoffrey, Ahmed, Osama, Owiti Rhoda, Wasunna, Monique, Edwards Tansy, Ahmed Musa, Rashid Juma, Eyasu Makonnen (157087), Ahmed Osama, Osama Ahmed, Lilian Apadet, Yifru, Sisay, Lilian Apadet (157060), Marius Mueller, Monique Wasunna, Yalemtsehay Mekonnen, Mbui, Jane, Simon Njoroge (157052), Workagegnehu Hailu (101983), Sally Ellis, Zewdu Hurissa (101992), Geoffrey Mucee (157047), Joseph Olobo, Josephine Kesusu (157113), Manduku, Veronica, Sally Ellis (157129), Dedan Mutea (157064), Kirigi George, El-Hassan, Ahmed, Hurissa, Zewdu, Mutuma, Geoffrey, Ahmed Fadlalla, Balasegaram, Manica, Wasunna Monique, Fadlalla Ahmed, Asrat Hailu (59005), Mekonnen, Yalemtsehay, Owiti, Rhoda, Ndegwa Serah, Apadet, Lilian, Veronica Manduku (157055), Mengistu Getahun, Weldegebreal, Teklu, Musa Ahmed, Dedan Mutea, Mutea, Dedan, Kimutai Robert, Veronica Manduku, Asrat Hailu, Geoffrey Mutuma, Monique Wasunna (157135), Abuzaid Abdalla Abuzaid, Manduku Veronica, Yalemtsehay Mekonnen (157084), Rhoda Owiti (157121), Josephine Kesusu, Patrick Sagaki, Manica Balasegaram (156987), Jane Mbui (157003), Hailu Workagegnehu, Makonnen Eyasu, Omollo, Raymond, Jane Mbui, Ahmed Fadlalla (157024), Mucee Geoffrey, Mueller, Marius, Lodenyo, Hudson, Getahun Mengistu, Tansy Edwards, Patrick Sagaki (157100), Manica Balasegaram, Khalil, Eltahir, Musa, Brima, Rashid, Juma, Mekonnen Yalemtsehay, Kirigi, George, Eyasu Makonnen, Musa Brima, Serah Ndegwa (157094), Abuzaid Abuzaid Abdalla, Ellis, Sally, Hailu, Asrat   +151 more
core   +1 more source

Leishmaniasis in the United States: Emerging Issues in a Region of Low Endemicity

Microorganisms, 2021
Leishmaniasis, a chronic and persistent intracellular protozoal infection caused by many different species within the genus Leishmania, is an unfamiliar disease to most North American providers.
John M. Curtin, Naomi E. Aronson
doaj   +1 more source

Kidney involvement in leishmaniasis—a review

Brazilian Journal of Infectious Diseases, 2014
Leishmaniasis is an infectious disease caused by protozoa of the genus Leishmania transmitted by insects of the genus Lutzomyia sp. or Phlebotomus sp.
Geraldo Bezerra da Silva Junior, Elvino José Guardão Barros, Elizabeth De Francesco Daher   +2 more
doaj   +1 more source

Visceral leishmaniasis in eastern Africa--current status. [PDF]

, 2007
Visceral leishmaniasis (VL) is among the most neglected of the tropical diseases, afflicting the poorest of the poor. In eastern Africa, VL causes at least 4000 deaths annually, a loss of approximately 385,000 disability-adjusted life years.
Reithinger, Richard, Brooker, Simon, Kolaczinski, Jan H   +2 more
core   +1 more source