Results 131 to 140 of about 23,618 (246)
Advances in Bio‐Integrated Edge Computing Systems for Smart and Connected Health
Advanced Materials, EarlyView.This review explores advances in bio‐integrated edge computing for healthcare, focusing on co‐designing computing, sensing, and energy strategies to overcome integration and power challenges for optimized, decentralized operation. ABSTRACT Recent advances in bio‐integrated healthcare technologies have enabled continuous, high‐resolution monitoring and ...
Gyuwon Kim +4 more
wiley +1 more source
Bacteria‐Trained, MnO2‐Armored Dendritic Cells for Immunotherapy
Advanced Materials, EarlyView.MnO2‐armored, bacteria‐trained dendritic cells undergo tumor‐responsive mechanical and immunological transformation. The nanocoating masks immune ligands and maintains a mechanically stiff, quiescent state during circulation, while the tumor microenvironment removes the armor and restores cellular deformability and immune accessibility.
Zhao Guo +9 more
wiley +1 more source
Piezo1 regulates the mechanotransduction of soft matrix viscoelasticity
Nature CommunicationsMechanosensitive ion channels such as Piezo1 have fundamental roles in sensing the mechanical properties of the extracellular matrix. However, whether and how Piezo1 senses time-dependent matrix mechanical properties, that is, viscoelasticity, remains ...
Mariana A. G. Oliva +11 more
doaj +1 more source
, 1997 The areas of suspension mechanics, stability and computational rheology have exploded in scope and substance in the last decade. The present book is one of the first of a comprehensive nature to treat these topics in detail.
Huilgol, R. R., Phan-Thien, Nhan.
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Mechanoactive Biomaterials for Cell–Matrix Mechanotransduction
Advanced Materials, EarlyView.The graphical abstract shows how individual triggers (force, light, or temperature) and combined optothermal or receptor‐targeted actuation induce material responses at the tissue, cellular, and receptor scales. Their spatial (global or focused) and temporal (continuous or cyclic) modulation determines the resulting mechanical output.
Yi‐Tung Lu +2 more
wiley +1 more source
Advanced Materials, EarlyView.A polymer blend of n‐type OMIEC P(gNDI‐gT2) with insulating PMMA yields mechanically stabilized, anti‐ambipolar organic electrochemical transistors (OECTs) with tunable ionic‐electronic transport. This blending allows low‐power, fast‐spiking heterogeneous Hodgkin–Huxley neurons, enabling biomimetic frequency deconvolution and reservoir computing, which
Zachary Laswick +12 more
wiley +1 more source
Advanced Materials, EarlyView.In this study, we show that retinal matrix stiffness is increased in diabetic mice. Using engineered human vascular models with controlled matrix stiffness, we demonstrate that stiffening activates focal adhesion kinase (FAK) signaling in pericytes, suppresses Notch signaling, and disrupts vascular morphology.
Emily Warren +6 more
wiley +1 more source
Advanced Materials, EarlyView.Defined PEG hydrogels enable human iPSC‐derived intestinal organoid culture without Matrigel. PEG‐ and Matrigel‐cultured organoids both support duodenal‐like epithelial identity, but direct comparison reveals subtle epithelial differentiation‐marker shifts and stronger mesenchymal ECM‐remodeling/integrin programs in PEG.
Alicja Kuziola +8 more
wiley +1 more source
Estimation of Internal Viscoelasticity by Mechanical Impedance
In evaluating the stiffness of skin surface, internal structures such as bone and muscle often affect the measurements. In the present paper, acoustic random vibration is used to estimated the viscoelasticity of a silicone-gel model. This viscoelasticity,
Nakamura, Takahiko, Oka, Hisao
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