Results 211 to 220 of about 261,480 (318)

Synthetic Hydrogels Incorporating Hydrolytic/Nonhydrolytic Macromer Ratios Exhibit Improved Tunability of In Vivo Degradation and Immune Responses

open access: yesAdvanced Healthcare Materials, EarlyView.
A synthetic 4‐arm maleimide‐terminated poly(ethylene glycol) (PEG‐4MAL) hydrogel system that combines hydrolytic ester‐linked macromer (PEG‐4eMAL) with nondegradable amide‐linked macromer (PEG‐4aMAL) in various stoichiometric ratios to tune the degradability rate. The macromers are crosslinked with dithiothreitol via thiol‐maleimide click reaction. The
Michael D. Hunckler   +7 more
wiley   +1 more source

Ascorbic Acid Modulates Collagen Properties in Glucocorticoid‐Induced Osteoporotic Bone: Insights into Chemical, Mechanical, and Biological Regulation

open access: yesAdvanced Healthcare Materials, EarlyView.
Osteoporosis from long‐term glucocorticoid (GIOP) use elevates susceptibility to fracture. This study shows GCs impair ascorbic acid (AA) metabolism in osteoblasts, collagen synthesis and extracellular matrix integrity. AA enhanced collagen biochemical and mechanical properties and restored osteoblast and endothelial function. These findings underscore
Micaila DE Curtis   +19 more
wiley   +1 more source

Natural‐Based Nanocomposite Ink Engineering for Seamless Multi‐Material Integration in Extrusion‐Based 3D Printing

open access: yesAdvanced Healthcare Materials, EarlyView.
This innovative ink engineering strategy enables the integration of bioactive nanocomposites into complex, multi‐material constructs. By combining primary chemical coupling and post‐printing photocuring, the study achieves tunable printability, seamless material integration, and robust mechanical performance.
João R. Maia   +7 more
wiley   +1 more source

Tunicate‐Inspired Carboxymethyl Cellulose Hydrogel Filler for Treating Age‐Associated Vocal Fold Atrophy

open access: yesAdvanced Healthcare Materials, EarlyView.
The pyrogallol‐conjugated carboxymethylcellulose (CMC‐PG) hydrogel is applicated as a filler for the treatment of presbylaryngis, a vocal fold atrophy. CMC‐PG provides a bulking effect to the vocal folds. CMC‐PG is readily injectable and tissue adhesive, enabling sustained release of growth factor over long period.
Jihoon Jeon   +7 more
wiley   +1 more source

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