Results 61 to 70 of about 405,931 (300)

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Visibility Requirements Engineering for Commercial Websites

open access: yes, 2014
Visibility in search engines is a competitive advantage of commercial websites. In this context, Search Engine Optimization (SEO) techniques are devised to enhance the ranking of websites in search engine results.
Mougouei, Davoud, Yeung, Man Kwan
core   +1 more source

Influence of Driver's Experience on Textual Traffic Sign Efficiency Depending on Visibility

open access: yesPromet (Zagreb), 2012
The research objective is to study the influence of thedriver's experience on the efficiency of the textual traffic sign dependingon the visibility, that is on the weather conditions.
Senka Pašagić   +2 more
doaj   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

Application of Fuzzy Techniques for Determining the Operating Speed Based on Road Geometry

open access: yesPromet (Zagreb), 2012
The operating speed is certainly one of the most important variables in the management of road safety. Its determination has been refined in the last few years by means of experimental analyses that have also sanctioned its strong link with the context ...
Antonino D'Andrea, Orazio Pellegrino
doaj   +1 more source

The Visibility of Value

open access: yesSocial Research: An International Quarterly, 2016
This paper gives an extended argument for the conclusion that values are visible properties in the world we inhabit (including nature) and are not entirely derivable from states of mind such as our desires and "moral sentiments." The argument thus repudiates as a superstition of modernity the widespread assumption that the concept of "nature" is to be ...
openaire   +2 more sources

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

open access: yesFEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil   +3 more
wiley   +1 more source

Linked Color Imaging of Barrett’s Esophageal Adenocarcinoma: Effects on Visibility

open access: yesGastroenterology Insights
Since linked color imaging (LCI) has been reported to increase the color differences in Barrett’s esophageal adenocarcinoma (BA) compared to white light imaging (WLI), a comparison of the visibility scores of various imaging techniques for BA is ...
Masahiro Saito   +10 more
doaj   +1 more source

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