Results 51 to 60 of about 8,543,121 (289)

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Research on Relay Technology of Visible Light Communication

open access: yesGuangtongxin yanjiu, 2021
As a beneficial supplement to radio frequency communication, Visible Light Communication (VLC) can provide highspeed, ultra-low delay, green, low-cost, safe and reliable communication services. However, limited coverage range has become the bottleneck of
Man-jing ZHU, Yu-hao WANG, Xiao-dong LIU
doaj   +1 more source

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

DMT modulation for VLC

open access: yes, 2022
S.133-180Introduction Optical free space communication using visible radiation, i.e. light, has been known for a very long time. Some early examples are signaling using fire, the Heliograph using sunlight, which is directed to the receiver by means of a ...
Langer, K.-D.
core   +1 more source

The C‐terminal region of KIF26B is indispensable for nephron progenitor condensation and kidney formation in mice

open access: yesFEBS Open Bio, EarlyView.
KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura   +19 more
wiley   +1 more source

Implementasi Visible Light Communication (VLC) Pada Sistem Komunikasi

open access: yesJurnal Elkomika, 2017
ABSTRAKPerkembangan teknologi telah menunjukkan peningkatan yang cukup signifikan, terutama untuk bidang komunikasi. Hal ini terbukti dengan banyaknya media komunikasi baik itu nirkabel dan kabel.
ARSYAD RAMADHAN DARLIS   +2 more
doaj   +1 more source

Power distribution investigation of a hexagonal diffused cellular indoor visible light communications system [PDF]

open access: yes, 2011
This paper presents a three dimensions (3D) model of optical power distribution in a diffused cellular indoor visible light communication (VLC) system.
Ghassemlooy, Zabih   +3 more
core  

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

open access: yesFEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay   +2 more
wiley   +1 more source

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