Results 81 to 90 of about 390,355 (301)

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Multimodal Stereo from Thermal Infrared and Visible Spectrum

ELCVIA Electronic Letters on Computer Vision and Image Analysis, 2014
Recent advances in thermal infrared imaging (LWIR) has allowed its use in applications beyond of the military domain. Nowadays, this new family of sensors is included in different technical and scientific applications. They offer features that facilitate
Fernando Barrera
doaj   +1 more source

UV–visible spectrum of the green synthesized selenium nanoparticles (SeNPs).

, 2023
UV–visible spectrum of the green synthesized selenium nanoparticles (SeNPs).
Muhammad Shahbaz (772838), Fozia Abasi (14581232), Noor Fatima (14581223), Kishwar Ali (14581226), Abida Akram (10131164), Naveed Iqbal Raja (10131161), Asma Mehak (12423563), Tariq Mukhtar (10368374), Maryam Ajmal (12423554), Nilofar Mustafa (14581229)   +9 more
core   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Visible spectrum and color

, 2016
Educação Superior::Ciências Exatas e da Terra::FísicaEnsino Médio::FísicaThe video explain what it means the visible spectrum, shows how our eyes can see the colors and and what would be a electromagnetic ...
National Aeronautics and Space Administration (NASA), Jet Propulsion Laboratory, California Institute of Technology   +2 more
core   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Visible spectrum and color

, 2011
Educação Superior::Ciências Exatas e da Terra::FísicaEnsino Médio::FísicaThe video explain what it means the visible spectrum, shows how our eyes can see the colors and and what would be a electromagnetic ...
National Aeronautics and Space Administration (NASA), Jet Propulsion Laboratory, California Institute of Technology   +2 more
core   +1 more source

Visible-Light Excitation of a Molecular Motor with an Extended Aromatic Core

, 2017
Exploring routes to visible-light-driven rotary motors, the possibility of red-shifting the excitation wavelength of molecular motors by extension of the aromatic core is studied.
Ben L. Feringa (1429174), Jasper Pol (3804346), Sander J. Wezenberg (1711942), Diederik Roke (1370913), Thomas van Leeuwen (1764103)   +4 more
core   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source