Results 41 to 50 of about 2,380,891 (267)

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Visual rehabilitation via microperimetry in patients with geographic atrophy: a pilot study

International Journal of Retina and Vitreous, 2017
Background Age-related macular degeneration (AMD) is the leading cause of blindness in the western world. As a consequence of AMD, patients develop structural damage that comprises the fovea and subsequently present loss of central vision, low visual ...
Juan Abel Ramírez Estudillo, Mario Isaías León Higuera, Sergio Rojas Juárez, Maria de Lourdes Ordaz Vera, Yessica Pablo Santana, Benito Celis Suazo   +5 more
doaj   +1 more source

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

FEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi, Zainab Quraishi, Shima Khezri Azizi Far, Madaleine Ward, Aidan Conway, Reem Abdulredha, Eman Mshari, Yousif A. Shamsaldeen   +7 more
wiley   +1 more source

Autorefraction, Retinoscopy, Javal’s Rule, and Grosvenor’s Modified Javal’s Rule: The Best Predictor of Refractive Astigmatism

Journal of Ophthalmology, 2016
The aim of the study was to determine the level of agreement between Javal’s rule, autorefraction, retinoscopy, and refractive astigmatism and to determine which technique is the most suitable substitute when subjective refraction is not applicable using
Kofi Asiedu, Samuel Kyei, Emmanuel Ekow Ampiah   +2 more
doaj   +1 more source

The Whole World in Your Hand: Active and Interactive Segmentation [PDF]

, 2003
Object segmentation is a fundamental problem in computer vision and a powerful resource for development. This paper presents three embodied approaches to the visual segmentation of objects. Each approach to segmentation is aided by the presence of a hand
Arsenio, Artur, Fitzpatrick, Paul, Kemp, Charles C., Metta, Giorgio   +3 more
core   +4 more sources

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Hydroxylation of organic substrate surfaces for the atomic layer deposition of Al2O3 thin films

Physics Open
The hydrophilicity of flexible organic substrates has a certain influence on the quality and performance of Al2O3 films prepared by atomic layer deposition (ALD). Surface treatment and other methods to improve the hydrophilicity of the substrate can make
Zixin Yang, Ziheng Hao, Guozheng Wang, Jianan Kang, Yang Luo, Zhiyuan Liu   +5 more
doaj   +1 more source

Functional interpretation of single cell similarity maps. [PDF]

, 2019
We present Vision, a tool for annotating the sources of variation in single cell RNA-seq data in an automated and scalable manner. Vision operates directly on the manifold of cell-cell similarity and employs a flexible annotation approach that can ...
Ashuach, Tal, DeTomaso, David, Jones, Matthew G, Subramaniam, Meena, Ye, Chun J, Yosef, Nir   +5 more
core  

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Patients with ocular trauma treated at the emergency department of the provincial hospital of Las Tunas, 2019

Revista Electrónica Dr. Zoilo E. Marinello Vidaurreta, 2021
Background: ocular traumas are one of the main causes of unilateral vision loss.Objective: to describe clinical and epidemiological characteristics of the patients with ocular trauma treated at the emergency department of the “Dr.
Mario Enrique Plá-Acebedo, María Cristina Cisneros-Vázquez, Brunilda de los Ángeles Abeleira-Ortiz, Elisabeth del Carmen Ramírez-Pérez, Henrry Agustín Mena-Silva   +4 more
doaj