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Bridging the gap of vision restoration [PDF]

open access: yesFrontiers in Cellular Neuroscience
Retinitis pigmentosa (RP) and Age-Related Macular Degeneration (AMD) are similar in that both result in photoreceptor degeneration leading to permanent progressive vision loss.
Maya Carleton   +3 more
doaj   +4 more sources

Innovative Optogenetic Strategies for Vision Restoration [PDF]

open access: yesFrontiers in Cellular Neuroscience, 2018
The advent of optogenetics has ushered in a new era in neuroscience where spatiotemporal control of neurons is possible through light application. These tools used to study neural circuits can also be used therapeutically to restore vision.
Cameron K. Baker, John G. Flannery
doaj   +4 more sources

Current approaches to vision restoration using optogenetic therapy [PDF]

open access: yesFrontiers in Cellular Neuroscience, 2023
Inherited progressive degeneration of photoreceptors such as retinitis pigmentosa (RP) is the most common cause of blindness leading to severe vision impairment affecting ~1 in 5,000 people worldwide.
Kashish Parnami, Anwesha Bhattacharyya
doaj   +2 more sources

Retinal Prostheses: Engineering and Clinical Perspectives for Vision Restoration

open access: yesSensors, 2023
A retinal prosthesis, also known as a bionic eye, is a device that can be implanted to partially restore vision in patients with retinal diseases that have resulted in the loss of photoreceptors (e.g., age-related macular degeneration and retinitis ...
Kevin Y. Wu   +4 more
doaj   +3 more sources

Destructive effects on endothelial cells of grafts in cytomegalovirus DNA-positive patients after keratoplasty [PDF]

open access: yesInternational Journal of Ophthalmology, 2023
AIM: To investigate corneal graft survival rate and endothelial cell density (ECD) loss after keratoplasty in cytomegalovirus (CMV) positive patients. METHODS: This was a retrospective cohort study. We analyzed the clinical data of patients who underwent
Yun-Xiao Zang   +8 more
doaj   +1 more source

Aldose reductase inhibition decelerates optic nerve degeneration by alleviating retinal microglia activation

open access: yesScientific Reports, 2023
As part of the central nervous system (CNS), retinal ganglion cells (RGCs) and their axons are the only neurons in the retina that transmit visual signals from the eye to the brain via the optic nerve (ON).
Mishal Rao   +11 more
doaj   +1 more source

Predictors of short-term outcomes related to central subfield foveal thickness after intravitreal bevacizumab for macular edema due to central retinal vein occlusion [PDF]

open access: yesInternational Journal of Ophthalmology, 2016
AIM: To investigate the predictive factors for short-term effects of intravitreal bevacizumab injections on central subfield foveal thickness (CSFT) in patients with macular edema (ME) secondary to central retinal vein occlusion (CRVO).
Mei-Zi Wang   +6 more
doaj   +1 more source

Evaluation of axial length/total corneal refractive power ratio as a potential marker for ocular diagnosis of Marfan’s syndrome in children [PDF]

open access: yesInternational Journal of Ophthalmology, 2021
AIM: To investigate whether the axial length (AL)/total corneal refractive power (TCRP) ratio is a sensitive and simple factor that can be used for the early diagnosis of Marfan's syndrome (MFS) in children.
Tian-Hui Chen   +8 more
doaj   +1 more source

Evaluation of the efficacy of laser peripheral iridoplasty in reversing the darkroom provocative test result in Chinese patients with primary angle closure status post laser iridotomy [PDF]

open access: yesInternational Journal of Ophthalmology, 2015
AIM: To investigate the efficacy and safety of krypton laser peripheral iridoplasty (LPIP) for Chinese patients with primary angle closure (PAC) or primary angle-closure glaucoma (PACG) status post laser iridotomy in reversing the positive results of the
Ping Huang, Ling-Ling Wu
doaj   +1 more source

Measurement of the depths at different regions of the anterior chamber in healthy Chinese adults [PDF]

open access: yesInternational Journal of Ophthalmology, 2020
AIM: To measure the depths of different regions of the anterior chamber (AC) in healthy Chinese adults, and to explore possible correlations with age or gender.
Yuan Zong   +5 more
doaj   +1 more source

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