Results 31 to 40 of about 283,540 (312)
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
Fundamentals of colour awareness: a literature review
African Vision and Eye Health, 2005 A description of some of the basic or funda-mental aspects of the colour sensory mechanism will be provided here, based on modern ideas and literature, with reference specifically to the likely origins and evolution of colour vision. The mo-lecular basis
A. Rubin
doaj +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Colour vision: A review of the Cambridge Colour Test and other colour testing methods
African Vision and Eye Health, 2015 The evaluation of colour vision and discrimination of an individual forms an integral part of a routine eye and vision examination. With the increasing prevalence of inherited colour vision deficiencies, defects of colour vision can be detected in an ...
Nabeela Hasrod, Alan Rubin
doaj +1 more source
Repeatability and Intercorrelations of Standard Vision Tests as a Function of Age [PDF]
, 2000 Purpose: We assessed repeatability and intercorrelations of five standard vision tests in subjects with normal vision. Methods: Seventy-eight subjects (aged 21 to 68 years) completed five measurements each of high- and low-contrast visual acuity, near
Lovie-Kitchin, Jan E., Brown, Brian
core
Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs
FEBS Open Bio, EarlyView.Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner +7 more
wiley +1 more source
Intraexaminer repeatability and agreement in stereoacuity measurements made in young adults [PDF]
International Journal of Ophthalmology, 2015 AIM: To determine the repeatability and agreement of stereoacuity measurements made using some of the most widely used clinical tests: Frisby, TNO, Randot and Titmus.
Beatriz Antona +4 more
doaj +1 more source
Assessment of age-related maculopathy using subjective vision tests [PDF]
, 2005 This paper reviews non-standard, clinical vision tests that may be used to detect the\ud earliest visual loss in age-related maculopathy (ARM), before fundus changes are\ud detected. We recommend a clinical test battery for all patients aged 60 years and
Lovie-Kitchin, Jan E., Feigl, Beatrix
core
New Directions for Adult and Continuing Education, EarlyView.ABSTRACT This article examines the evolving role of organizational leadership amidst the rapid advancements in artificial intelligence (AI). It explores a broadly experienced and documented crisis in leadership, due in part to the disruptive nature of AI and emerging technology.
Rachel Wlodarsky, Davin Carr Chellman
wiley +1 more source
Performance of a Rapid Rarebit Central-Vision Test with Optic Neuropathies [PDF]
, 2012 Purpose. Rarebit vision tests probe for gaps in the neuro-retinal receptive field matrix, using bright micro dots on a dark background. Previous reports have found central-vision rarebit tests useful for macular lesions. Their performance with lesions of
Frisén, Lars,
core +1 more source