Results 141 to 150 of about 157,576 (265)

Switching disease‐modifying therapies in patients with spinal muscular atrophy: A systematic review on effectiveness outcomes

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
With multiple disease‐modifying therapies now available, treatment switching has become an important clinical consideration in the management of spinal muscular atrophy (SMA). While some switches are prompted by suboptimal clinical response, more commonly they are driven by treatment burden, convenience, or adverse events.
Andrej Belančić   +4 more
wiley   +1 more source

A multi-agent simulation approach to sustainability in tourism development [PDF]

open access: yes
In the last decades the increasing facility in moving and the simultaneous fall of the transportation costs have strongly increased the tourist flows. As a consequence, different destinations, especially those which are rich of natural resources, unable ...
Elena Maggi   +2 more
core  

Cost‐utility analysis of nusinersen–risdiplam switch in patients with spinal muscular atrophy in Croatia: A discrete event simulation model

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Introduction In recent years, the treatment of spinal muscular atrophy (SMA), a rare disease, has significantly progressed, improving patients' survival and overall quality of life. However, current SMA treatments are expensive, and some (nusinersen) are very inconvenient for patients.
Andrej Belančić   +4 more
wiley   +1 more source

Empowering citizens to spontaneously report suspected adverse drug reaction: Systematic literature review of interventions and their impact

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
This systematic literature review aimed to identify and characterize existing interventions designed to empower citizens to spontaneously report adverse drug reactions (ADRs) and to determine which interventions have been shown to be the most effective internationally. The research question was structured using the PICO framework.
Margarida Perdigão   +3 more
wiley   +1 more source

Quality indicators for safe and effective medication use in long‐term care facilities: A modified Delphi study

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aim This modified Delphi study aimed to achieve expert agreement on quality indicators (QIs) suitable for application at the population level, to evaluate quality use of medications and pharmacist services in long‐term care facilities (LTCFs). Methods We conducted a two‐round modified online Delphi study with a multidisciplinary panel of Australian ...
Daria S. Gutteridge   +10 more
wiley   +1 more source

EKSPEKTASI DAN PERSEPSI WISATAWAN TERHADAP KUALITAS PELAYANAN PADA MARINA SRIKANDI TOUR & TRAVEL DI PADANGBAI

open access: yesJurnal IPTA, 2013
Differences between expectation and perception of visitor about service quality of a travel agency were the background of this research which is entitled “Visitor’s Perception And Expectation of Service Quality At Marina Srikandi Tour And Travel In ...
Made Natha Dwipayana   +2 more
doaj  

The quality of interaction with children in collective play: Children's agency

open access: yesBritish Educational Research Journal, EarlyView.
Abstract There is a growing body of studies on increasing the quality of infant–toddler education and care. Yet little attention has been directed towards how to bring toddlers' agency and perspective to their personally meaningful learning in collective play.
Liang Li
wiley   +1 more source

Impact of a One‐Week Bioengineering Outreach Activity on the Academic Perceptions and Motivation of High School Students

open access: yesBiochemistry and Molecular Biology Education, EarlyView.
ABSTRACT Many universities across Europe have developed outreach programs to bring high school students closer to science and help them make more informed decisions about their academic futures. At the University of Porto (Portugal), the Junior University is a summer school that offers research and development activities on specific topics, enabling ...
J. S. Sousa   +6 more
wiley   +1 more source

Classifying avian drinking behaviour: ecological insights and implications in a changing world

open access: yesBiological Reviews, EarlyView.
ABSTRACT Water is a fundamental currency of life, and its availability significantly influences animal behaviour, physiology and distributions. However, our knowledge around the dependence on water for drinking and the direct and indirect mechanisms driving related behaviours remains partial in the context of changing climates. Here, we review patterns
Shannon R. Conradie, Marc T. Freeman
wiley   +1 more source

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