Results 91 to 100 of about 137,910 (297)

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source

FREQUENCY AND INTENSITY OF SHOULDER PAIN AFTER STROKE: A HOSPITAL BASED STUDY

Pakistan Armed Forces Medical Journal, 2017
Objective: To determine the frequency and intensity of shoulder pain in stroke patients and explore any relation of shoulder pain with the side of involvement and the primary etiology of stroke. Study Design: A cross-sectional descriptive study.
Uzma Akhlaq, Saeed Bin Ayaz, Noreen Akhtar, Atif Ahmed Khan   +3 more
doaj   +2 more sources

Comparison of Local Infection, Dwell Time and Pain in Peripheral Venous Cannulation passed by Experts versus General Inserters at a Tertiary Care Hospital

Pakistan Armed Forces Medical Journal
Objective: To compare the incidence of local infection, Dwell time and pain associated with peripheral venous cannulation (PVC) when performed by experts versus general inserters in a tertiary care hospital.
Elleyyeen Avais, Syed Anees Ahmed Gardezi, Muhammad Uzair, Muhammad Iqbal, Hassan Javed   +4 more
doaj   +1 more source

An alternative visual analogue scale [PDF]

Anaesthesia, 1982
M, Bahar, D M, McAuley, J W, Dundee
openaire   +2 more sources

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus

FEBS Open Bio, EarlyView.
BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima, Gustavo Narvaes Guimarães, Emilyane de Oliveira Santana Amaral, Bianca Caroline Figueiredo Bianco, Manuel Jara‐Espejo, Sérgio Roberto Peres Line, Ana Paula de Souza, Aline Cristiane Planello   +7 more
wiley   +1 more source

Spinal manipulative therapy versus Graston Technique in the treatment of non-specific thoracic spine pain: design of a randomised controlled trial [PDF]

, 2008
Background: The one year prevalence of thoracic back pain has been estimated as 17% compared to 64% for neck pain and 67% for low back pain. At present only one randomised controlled trial has been performed assessing the efficacy of spinal manipulative ...
Simon D French, Crothers, A., French, S.D., Amy Crothers, Bruce Walker, Walker, B, Crothers, A, Walker, B.F., French, SD   +8 more
core   +2 more sources

Prevalence of refractory and unexplained chronic cough in adults treated in cough centre

ERJ Open Research
Background Refractory chronic cough and unexplained chronic cough pose significant clinical challenges, impairing patients’ quality of life. However, a precise definition of refractory chronic cough remains elusive.
Paweł Kukiełka, Katarzyna Moliszewska, Katarzyna Białek-Gosk, Elżbieta M. Grabczak, Marta Dąbrowska   +4 more
doaj   +1 more source

Benzydamine gargle versus ketamine gargle for postoperative sore throat

Medicine Science, 2018
Postoperative sore throat is usually accepted as a minor complication, however it contributes to patient dissatisfaction. The primary aim of this study is to compare the effects of two different therapies for postoperative sore throat.
Basak Altiparmak, Mustafa Turan
doaj   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi, Lara Basovic, Christopher Michael McGraw   +2 more
wiley   +1 more source